Clinical and biochemical characteristics of high-intensity functional training (HIFT) and overtraining syndrome: findings from the EROS study (The EROS-HIFT)

Journal of Sports Sciences
Flavio A CadegianiMatheus Gazola

Abstract

The metabolic and hormonal consequences of high-intensity functional training regimens such as CrossFit® (CF) are unclear. Little is known about the triggers and clinical and biochemical features of CF-related overtraining syndrome (OTS). The EROS study compared endocrine and metabolic responses, and eating, social, psychological and body characteristics of OTS-affected (OTS) and healthy athletes (ATL), and non-physically active controls (NPAC). The current study is a post-hoc analysis of the CF subgroups of the EROS study, to evaluate specific characteristics of CF in ATL and OTS. Parameters were overall and pairwise compared among OTS-affected (CF-OTS) and healthy (CF-ATL) athletes that exclusively practiced CF, and NPAC. CF-ATL yielded earlier and enhanced cortisol, GH, and prolactin responses to an insulin tolerance test (ITT), increased neutrophils, lower lactate, increased testosterone, improved sleep quality, better psychological performance, increased measured-to-predicted basal metabolic rate (BMR) ratio and fat oxidation, and better hydration, when compared to NPAC. Conversely, more than 90% of the adaptive changes in CF were lost under OTS, including an attenuation of the hormonal responses to an ITT, increased estra...Continue Reading

References

Oct 24, 2013·Journal of Strength and Conditioning Research·Julie A PartridgeBrittany D Massengale
Sep 5, 2015·Journal of Strength and Conditioning Research·Kliszczewicz M BrianBrandi M Price
Nov 12, 2015·Journal of Human Kinetics·Brian KliszczewiczJ Kyle Taylor
Nov 3, 2016·The Physician and Sportsmedicine·Valentina PerciavalleMarinella Coco
Sep 16, 2016·Orthopaedic Journal of Sports Medicine·Jan W C SpreyClaudio Santili
Nov 17, 2016·Military Medicine·Christopher K HaddockNattinee Jitnarin
Apr 1, 2017·Workplace Health & Safety·Jena MeyerJulie Zuniga
May 5, 2017·Journal of Human Kinetics·Chen-Kang ChangPo-Ju Lin
May 18, 2017·American Journal of Physiology. Endocrinology and Metabolism·Stephan NieuwoudtJohn P Kirwan

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Citations

Jul 1, 2020·Journal of Sports Sciences·Lee BellDavid Rogerson
Jul 25, 2019·International Journal of Environmental Research and Public Health·Rodrigo PoderosoJosé Vilaça-Alves
Dec 4, 2020·PloS One·João Henrique GomesLucindo José Quintans-Júnior
Jan 7, 2021·International Journal of Sports Physiology and Performance·Flavio A CadegianiClaudio E Kater
Jul 7, 2021·Metabolomics : Official Journal of the Metabolomic Society·Alain ParisYves Le Bouc
Sep 10, 2021·Sports Health·Justin CarrardArno Schmidt-Trucksäss
Dec 7, 2021·Revista brasileira de ginecologia e obstetrícia : revista da Federação Brasileira das Sociedades de Ginecologia e Obstetrícia·Maita Poli de AraujoManoel João Batista Castello Girão

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Software Mentioned

EROS
PROFILE
SPSS
Cross
BASAL
STRESS
Fit®
Crossfit

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