PMID: 9429858Jan 16, 1998Paper

Clinical and biochemical evaluation of Cushing's syndrome

Endocrinology and Metabolism Clinics of North America
C A Meier, B M Biller

Abstract

Over the past decade, several advances have been made in our understanding of the molecular pathogenesis of pituitary adenomas, and novel diagnostic tests for the diagnosis and differential diagnosis of Cushing's syndrome have been developed. Although established in the late 1970s, measurement of UFC has emerged as the most sensitive and specific test to screen for and confirm the presence of Cushing's syndrome. The combined CRH/DST is potentially a useful adjunct in patients with probable pseudo-Cushing's syndrome and borderline elevated urinary cortisol levels. Improved assays for circulating ACTH levels are now used as the first test in differentiating ACTH-dependent from ACTH-independent sources. HDDST with the revised reference ranges for UFC currently remains the primary test for differentiating pituitary from ectopic ACTH secretion. However, the CRH test may replace the HDDST in the foreseeable future because of its lower rate of false-positive and false-negative results. IPSS has been established as an integral part of the evaluation of patients with suspected Cushing's disease and no conclusive (> 0.8 to 1 cm) pituitary adenoma. Advances in the radiolabeling of small peptides, such as somatostatin analogs, may facilita...Continue Reading

References

Oct 12, 1979·JAMA : the Journal of the American Medical Association·S W LambertsJ C Birkenhäger
Sep 1, 1979·Metabolism: Clinical and Experimental·L Crapo
Oct 1, 1992·The New England Journal of Medicine·A LacroixR Taillefer
Sep 26, 1991·The New England Journal of Medicine·D N Orth
Jan 11, 1991·AJR. American Journal of Roentgenology·J L DoppmanG P Chrousos
Apr 1, 1991·Clinical Endocrinology·P J Trainer, A Grossman
Jun 1, 1991·The Journal of Clinical Endocrinology and Metabolism·G S Wand, A S Dobs
Mar 15, 1990·Annals of Internal Medicine·T B Kaye, L Crapo
Jun 15, 1990·Annals of Internal Medicine·M E Molitch, E J Russell
Feb 1, 1988·The Journal of Clinical Endocrinology and Metabolism·M H LaudatJ P Luton
Aug 18, 1988·The New England Journal of Medicine·P W GoldG P Chrousos
Sep 1, 1988·Journal of Computer Assisted Tomography·J L DoppmanD L Loriaux
Aug 11, 1988·The New England Journal of Medicine·P W GoldG P Chrousos
Sep 1, 1988·The American Journal of Psychiatry·J H MendelsonJ Ellingboe
Sep 1, 1986·AJR. American Journal of Roentgenology·J W ReinigJ Frank
Jan 1, 1986·Radiology·J W ReinigR H Knop
Jan 1, 1986·The American Journal of Medicine·A H Vagnucci, E Evans
May 1, 1986·The Journal of Clinical Endocrinology and Metabolism·L N ContrerasJ B Tyrrell
Jun 15, 1968·British Medical Journal·C K ConnollyM R Wills
Jun 1, 1983·Annals of Internal Medicine·P M Copeland
Nov 1, 1984·The American Journal of Medicine·R SakiyamaA J Van Herle
Apr 1, 1995·Baillière's Clinical Endocrinology and Metabolism·C TsigosG P Chrousos
Dec 1, 1993·Annals of Internal Medicine·G P ChrousosM Karl
Jan 1, 1996·Annual Review of Medicine·C Tsigos, G P Chrousos

❮ Previous
Next ❯

Citations

Dec 31, 2005·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Rana F AmmouryEwa Elenberg
Jun 15, 2010·Reviews in Endocrine & Metabolic Disorders·Krystallenia I Alexandraki, Ashley B Grossman
Jul 22, 2008·Clinics in Dermatology·Batya B DavidoviciRonni Wolf
Feb 26, 2000·International Journal of Dermatology·S A Jabbour, J L Miller
Jul 8, 2010·Clinical Chemistry and Laboratory Medicine : CCLM·Silvia PersichilliCecilia Zuppi
May 17, 2007·Srpski arhiv za celokupno lekarstvo·Zorana PenezićMilka Drezgić
Jun 12, 2004·Neurosurgical Focus·Marie Simard
Feb 16, 2011·Bioanalysis·Dong Sheng MingTeri-Lynn Bajkov
Jan 27, 2009·Journal of Endocrinological Investigation·L VilarL A Casulari
Sep 26, 2013·International Journal of Endocrinology·Shih-Chen TungTao-Chen Lee
Mar 11, 2005·Endocrine Journal·Huy Anh Tran, Nikolai Petrovsky
Dec 24, 2014·Pituitary·Odelia Cooper
Jan 23, 2008·Arquivos brasileiros de endocrinologia e metabologia·Lucio VilarOscar D Bruno
Jan 23, 2008·Arquivos brasileiros de endocrinologia e metabologia·Lucio VilarClaudio E Kater
May 26, 2004·Clinics in Laboratory Medicine·Jennifer P HolstSteven J Soldin
Dec 19, 2006·Clinica Chimica Acta; International Journal of Clinical Chemistry·Hitoshi HorieNorihiko Aoki
Dec 20, 2002·Obesity Research·Rosane Ness-AbramofLouis Shenkman
Sep 29, 2006·Expert Review of Anticancer Therapy·Rebecca L Brown, Roy E Weiss
Mar 27, 2004·Clinical Chemistry·K C Allen ChanChristopher W K Lam
Apr 15, 2004·Endocrine Reviews·Georg MansmannStefan R Bornstein
Mar 12, 2005·Arquivos brasileiros de endocrinologia e metabologia·Antônio C RubatinoIngeborg Christa Laun
Jul 11, 2000·Hospital Practice·N S ReauE L Mazzaferri
Feb 27, 2003·Journal of Endocrinological Investigation·C EremE Sencer
Apr 12, 2003·American Journal of Clinical Dermatology·Serge A Jabbour
Oct 30, 2003·Endocrine Practice : Official Journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists·Farhad ZangenehFereydoun Zangeneh

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Endocrinology and Metabolism Clinics of North America
J W Findling, H Raff
Endocrinology and Metabolism Clinics of North America
J W Findling, H Raff
© 2021 Meta ULC. All rights reserved