Clinical and cytological study of the oral mucosa of smoking and non-smoking qat chewers in Yemen

Clinical Oral Investigations
M HijaziT W Remmerbach

Abstract

The study was conducted to investigate the role of qat and smoking habits on the prevalence of visible and cytological abnormalities in the oral mucosa among Yemenites. We recruited 30 non-smoking and 30 smoking Yemenites chewing qat unilaterally for at least 5 years. We inspected oral cavities for the presence of lesions and took brush biopsies from the buccal mucosa/gingiva of the chewing/non-chewing region. All visible oral lesions were flat and homogeneous, and cytological changes were detected frequently. Among both non-smokers and smokers, white lesions and cytological changes were detected in 77% of all cases. On the chewing area, the proportion with white lesions ranged--depending on anatomical area and smoking status--between 47 and 93% and was significantly more frequent than on the non-chewing side (range 3-47%). The proportion of regions with changes was similar in non-smokers and smokers. Kappa statistics for "interobserver" agreement between visual inspection and cytological specimens of brush biopsies was at best fair (≤0.25). The high prevalence of visible lesions and cytological abnormalities among qat chewers was independent of smoking status. The moderate level of agreement between visual inspection and exfol...Continue Reading

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Citations

Nov 28, 2017·Journal of Investigative and Clinical Dentistry·Sadeq A Al-MaweriAmany Sharhan
Dec 8, 2017·Journal of Pharmaceutical Policy and Practice·Ammar Ali Saleh JaberSyed Azhar Syed Sulaiman
Sep 2, 2017·Diagnostic Cytopathology·Adile Ferda DagliSuleyman Aydin
Aug 24, 2017·Journal of Investigative and Clinical Dentistry·Sadeq A Al-MaweriAbdulaziz Samran
Nov 16, 2019·Substance Use & Misuse·Mohammed AlshakkaMohamed Izham Mohamed Ibrahim

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