Clinical and demographic characteristics of psychiatric patients seropositive for Borrelia burgdorferi

European Psychiatry : the Journal of the Association of European Psychiatrists
Tomás HájekCyril Höschl

Abstract

Borrelia burgdorferi (Bb) infection can affect the central nervous system and possibly lead to psychiatric disorders. We compared clinical and demographic variables in Bb seropositive and seronegative psychiatric patients and healthy controls. Nine hundred and twenty-six consecutive psychiatric patients were screened for antibodies to Bb and compared with 884 simultaneously recruited healthy subjects. Contrary to healthy controls, seropositive psychiatric patients were significantly younger than seronegative ones. None of the studied psychiatric diagnostic categories exhibited stronger association with seropositivity. There were no differences between seropositive and seronegative psychiatric patients in hospitalization length, proportion of previously hospitalized patients and proportion of subjects with family history of psychiatric disorders. These findings elaborate on potential association between Bb infection and psychiatric morbidity, but fail to identify any specific clinical 'signature' of Bb infection.

References

Jun 1, 1989·Neurology·J J HalperinR J Dattwyler
Jun 18, 1982·Science·W BurgdorferJ P Davis
Nov 1, 1994·The American Journal of Psychiatry·B A Fallon, J A Nields
Jul 1, 1994·The Journal of Clinical Investigation·S E SchutzerM Brunner
Jul 1, 1993·Clinics in Dermatology·W Kristoferitsch
Jan 1, 1997·Annual Review of Immunology·L H Sigal
Jun 9, 1998·Journal of Neurology·R Kaiser
Feb 1, 2000·Zentralblatt Für Bakteriologie : International Journal of Medical Microbiology·F Strle
Feb 2, 2002·The American Journal of Psychiatry·Tomás HájekCyril Höschl
Oct 16, 2002·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·George Bartzokis
Aug 21, 2003·The Journal of Neuropsychiatry and Clinical Neurosciences·Brian A FallonJ John Mann

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Citations

Mar 16, 2007·Médecine et maladies infectieuses·T Papo
Aug 30, 2008·Nordic Journal of Psychiatry·Hans Joergen GrabeHenry Völzke
Sep 12, 2019·Healthcare·Robert C BransfieldDouglas R Bransfield

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