Clinical and economic burden associated with cardiovascular events among patients with hyperlipidemia: a retrospective cohort study

BMC Cardiovascular Disorders
K M FoxOnur Baser

Abstract

Annual direct costs for cardiovascular (CV) diseases in the United States are approximately $195.6 billion, with many high-risk patients remaining at risk for major cardiovascular events (CVE). This study evaluated the direct clinical and economic burden associated with new CVE up to 3 years post-event among patients with hyperlipidemia. Hyperlipidemic patients with a primary inpatient claim for new CVE (myocardial infarction, unstable angina, ischemic stroke, transient ischemic attack, coronary artery bypass graft, percutaneous coronary intervention and heart failure) were identified using IMS LifeLink PharMetrics Plus data from January 1, 2006 through June 30, 2012. Patients were stratified by CV risk into history of CVE, modified coronary heart disease risk equivalent, moderate- and low-risk cohorts. Of the eligible patients, propensity score matched 243,640 patients with or without new CVE were included to compare healthcare resource utilization and direct costs ranging from the acute (1-month) phase through 3 years post-CVE date (follow-up period). Myocardial infarction was the most common CVE in all the risk cohorts. During the acute phase, among patients with new CVE, the average incremental inpatient length of stay and ...Continue Reading

References

Feb 1, 1992·Journal of Clinical Epidemiology·M Von KorffK Saunders
May 23, 2001·JAMA : the Journal of the American Medical Association·UNKNOWN Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults
Jan 13, 2006·Circulation·Thomas ThomUNKNOWN American Heart Association Statistics Committee and Stroke Statistics Subcommittee
Jul 4, 2007·Health Promotion Practice·Justin G TrogdonDiane Orenstein
Jul 16, 2008·Journal of Clinical Epidemiology·Mary E CharlsonJames P Hollenberg
Apr 23, 2010·Journal of the American Society of Hypertension : JASH·Mei Sheng DuhSiew Hwa Ong
Aug 3, 2010·Journal of Medical Economics·Robert L OhsfeldtMichael Davidson
Mar 18, 2011·BMC Cardiovascular Disorders·Richard H ChapmanRobert J Straka
May 19, 2011·PharmacoEconomics·Amy K O'SullivanDavid Thompson
Apr 27, 2012·Globalization and Health·Michael M EngelgauAjay Mahal
Jan 10, 2013·Circulation. Cardiovascular Quality and Outcomes·Charalambos V VlachopoulosChristodoulos I Stefanadis
Dec 20, 2013·Circulation·Alan S GoUNKNOWN American Heart Association Statistics Committee and Stroke Statistics Subcommittee
Mar 13, 2014·Tropical Medicine & International Health : TM & IH·Anup KaranAjay Mahal
Jun 22, 2014·General Hospital Psychiatry·Chieh-Sen ChuangChia-Hung Kao
Jun 25, 2014·Nature Reviews. Cardiology·Razvan T Dadu, Christie M Ballantyne
Dec 19, 2014·Circulation·Dariush MozaffarianUNKNOWN American Heart Association Statistics Committee and Stroke Statistics Subcommittee

❮ Previous
Next ❯

Citations

Jan 18, 2019·Circulation Research·Natalie C WardRobert H Eckel
Jan 13, 2018·Molecular Genetics and Genomics : MGG·Xu LinHong-Wen Deng
Dec 20, 2017·Circulation·Shakira F SugliaUNKNOWN American Heart Association Council on Epidemiology and Prevention; Council on Cardiovascular Disease in the Young; Council o
Aug 31, 2017·Journal of Managed Care & Specialty Pharmacy·Rolin L WadeDavid J Harrison
Sep 5, 2017·Clinical Psychology : a Publication of the Division of Clinical Psychology of the American Psychological Association·Archana BasuKarestan C Koenen
Jan 20, 2020·Cardiovascular Revascularization Medicine : Including Molecular Interventions·Soeren MattkeDavid E Kandzari
Nov 18, 2018·Romanian Journal of Internal Medicine = Revue Roumaine De Médecine Interne·Hilal YücelAhmet Bedri Özer
Oct 26, 2021·Public Health Nutrition·Benjamin YarnoffLaurel Bates

❮ Previous
Next ❯

Methods Mentioned

BETA
coronary artery bypass

Software Mentioned

SAS®

Related Concepts

Related Feeds

Brain Ischemia

Brain ischemia is a condition in which there is insufficient blood flow to the brain to meet metabolic demand. Discover the latest research on brain ischemia here.