Clinical and economic outcomes for patients with health care-associated Staphylococcus aureus pneumonia.

Journal of Clinical Microbiology
Andrew F ShorrGerry Oster

Abstract

While the increasing importance of methicillin-resistant Staphylococcus aureus (MRSA) as a pathogen in health care-associated S. aureus pneumonia has been documented widely, information on the clinical and economic consequences of such infections is limited. We retrospectively identified all patients admitted to a large U.S. urban teaching hospital between January 2005 and May 2008 with pneumonia and positive blood or respiratory cultures for S. aureus within 48 h of admission. Among these patients, those with suspected health care-associated pneumonia (HCAP) were identified using established criteria (e.g., recent hospitalization, admission from nursing home, or hemodialysis). Subjects were designated as having methicillin-resistant (MRSA) or methicillin-susceptible (MSSA) HCAP, based on initial S. aureus isolates. Initial therapy was designated "appropriate" versus "inappropriate" based on the expected susceptibility of the organism to the regimen received. We identified 142 patients with evidence of S. aureus HCAP. Their mean (standard deviation [SD]) age was 64.5 (17) years. Eighty-seven patients (61%) had initial cultures that were positive for MRSA. Most ( approximately 90%) patients received appropriate initial antibioti...Continue Reading

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Citations

Mar 15, 2011·BMC Infectious Diseases·Ji Ye JungYoung Ae Kang
Nov 25, 2014·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Sarah S LewisDeverick J Anderson
Jul 30, 2011·International Journal of Antimicrobial Agents·Håkan HanbergerUNKNOWN EPIC II Group of Investigators
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Aug 17, 2019·Antimicrobial Resistance and Infection Control·Xuemei ZhenHengjin Dong
Jan 11, 2020·Open Medicine·Franca VergalitoRoberto Di Marco

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