Clinical and electrographic findings in epileptic vertigo and dizziness: a systematic review

Neurology
Alexander A TarnutzerDavid E Newman-Toker

Abstract

Seizures can cause vestibular symptoms, even without obvious epileptic features. We sought to characterize epileptic vertigo or dizziness (EVD) to improve differentiation from nonepileptic causes, particularly when vestibular symptoms are the sole manifestation. We conducted a systematic review with electronic (Medline) and manual search for English-language studies (1955-2014). Two independent reviewers selected studies. Study/patient characteristics were abstracted. We defined 3 study population types: (1) seizures, some experiencing vertigo/dizziness (disease cohort); (2) vertigo/dizziness, some due to seizures (symptom cohort); (3) vertigo/dizziness due to seizures in all patients (EVD-only cohort). We identified 84 studies describing 11,354 patients (disease cohort = 8,129; symptom cohort = 2,965; EVD-only cohort = 260). Among 1,055 EVD patients in whom a distinction could be made, non-isolated EVD was present in 8.5%, isolated EVD in 0.8%. Thorough diagnostic workups (ictal EEG, vestibular testing, and brain MRI to exclude other causes) were rare (<0.1%). Ictal EEG was reported in 487 (4.3%), formal neuro-otologic assessment in 1,107 (9.7%). Localized EEG abnormalities (n = 350) were most frequently temporal (79.8%) and u...Continue Reading

Citations

Oct 6, 2017·F1000Research·Masao NagayamaMitsuru Kawamura
May 29, 2019·Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology·Cleo DhondtIngeborg Dhooge
Jul 26, 2017·Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology·Sherifa A HamedAmira M Oseilly
Aug 26, 2017·Expert Opinion on Drug Safety·Sherifa A Hamed
Jan 1, 2016·Journal of Vestibular Research : Equilibrium & Orientation·Michael StruppThomas Brandt
Oct 6, 2017·Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova·M V Zamergrad, O S Levin
Jan 4, 2021·Epilepsy & Behavior : E&B·Wesley T KerrJohn M Stern
May 9, 2021·International Journal of Pediatric Otorhinolaryngology·Ozlem Gedik-SoyuyuceNazim Korkut
Sep 6, 2021·Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova·G V SelitskyA S Zherdeva

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