PMID: 9420316Jan 7, 1998Paper

Clinical and epidemiologic features of a massive waterborne outbreak of cryptosporidiosis in persons with HIV infection

Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology : Official Publication of the International Retrovirology Association
H R FrisbyJ P Davis

Abstract

During March and April 1993, a massive outbreak of Cryptosporidium infection resulted from contamination of the public water supply in Milwaukee, Wisconsin. The health impact of this outbreak in HIV-infected persons was unknown but was perceived as severe. We surveyed HIV-infected persons who resided in the greater Milwaukee area to examine the acute health impact of cryptosporidiosis on this population. Data from a random-digit dialing survey in the general population residing in the same area were used for comparison. The attack rate of watery diarrhea suggestive of cryptosporidiosis was lower in HIV-infected persons (32%) than in the general population (51%). There was no significant difference in attack rate in HIV-infected persons based on CD4+ T-lymphocyte count. In persons with watery diarrhea, HIV-infected persons were more likely to experience cough (42%), fever (52%), and dehydration (55%). In HIV-infected persons with watery diarrhea, persons with CD4+ T-lymphocyte counts <200/microl had longer duration of diarrhea and were more likely to seek medical attention and be hospitalized. During this massive waterborne outbreak, HIV-infected persons were not more likely to experience symptomatic Cryptosporidium infection th...Continue Reading

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Citations

Dec 13, 2000·International Journal for Parasitology·R FayerS J Upton
Sep 8, 2005·Journal of Clinical Gastroenterology·Allen C ChengNathan M Thielman
Apr 19, 2003·Emerging Infectious Diseases·Phaedra S CorsoAnne C Haddix
Dec 5, 2013·Journal of the Royal Army Medical Corps·Ralf Matthias HagenH Frickmann
Feb 19, 2005·American Journal of Epidemiology·John M ColfordDeborah A Levy
Oct 30, 2004·Scandinavian Journal of Infectious Diseases·Mette Vinther SkriverHenrik Toft Sørensen
Oct 24, 1998·The Medical Journal of Australia·M I SinclairM E Hellard
Jul 30, 2005·Scandinavian Journal of Infectious Diseases·Mona InsulanderBo Svenungsson

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