Clinical and epidemiological features of respiratory virus infections in preschool children over two consecutive influenza seasons in southern Brazil.

Journal of Medical Virology
Heloisa I G GiamberardinSonia M Raboni

Abstract

This study reports the results of a systematic screening for respiratory viruses in pediatric outpatients from an emergency department (ED) in southern Brazil during two consecutive influenza seasons. Children eligible for enrollment in this study were aged 24-59 months and presented with acute respiratory symptoms and fever. Naso- and oropharyngeal swabs were collected and multiplex reverse transcription PCR (RT-PCR) was performed to identify the respiratory viruses involved. In total, 492 children were included in this study: 248 in 2010 and 244 in 2011. In 2010, 136 samples (55%) were found to be positive for at least one virus and the most frequently detected viruses were human rhinovirus (HRV) (18%), adenovirus (AdV) (13%), and human coronavirus (CoV) (5%). In 2011, 158 samples (65%) were found to be positive for at least one virus, and the most frequently detected were HRV (29%), AdV (12%), and enterovirus (9%). Further, the presence of asthma (OR, 3.17; 95% CI, 1.86-5.46) was independently associated with HRV infection, whereas fever was associated with AdV (OR, 3.86; 95% CI, 1.31-16.52) and influenza infections (OR, 3.74; 95% CI, 1.26-16.06). Ten patients (2%) were diagnosed with pneumonia, and six of these tested posit...Continue Reading

References

Jan 29, 2000·The New England Journal of Medicine·H S IzurietaK Fukuda
Dec 3, 2005·The Journal of Infection·Luine R R V TsuchiyaMarilda M Siqueira
Jan 30, 2007·The Pediatric Infectious Disease Journal·Dominique PloinDaniel Floret
Jul 13, 2007·The Brazilian Journal of Infectious Diseases : an Official Publication of the Brazilian Society of Infectious Diseases·M C CoelhoS M Raboni
May 8, 2008·The Medical Journal of Australia·Katina D'Onise, Jane C A Raupach
Jan 13, 2010·Clinical Microbiology Reviews·John S Tregoning, Jürgen Schwarze
Dec 17, 2010·The New England Journal of Medicine·Romina LibsterFernando P Polack
Jan 13, 2011·Memórias do Instituto Oswaldo Cruz·Maria C DeburSonia M Raboni
Feb 23, 2011·Memórias do Instituto Oswaldo Cruz·Diogo André PilgerSandra Leistner-Segal
Mar 5, 2011·The Lancet Infectious Diseases·Bradford D GessnerSylvie Briand
Sep 13, 2011·American Journal of Infection Control·Aaron M MilstoneAlexandra Valsamakis
Jul 16, 2013·Journal of Clinical Microbiology·Q LepillerF Stoll-Keller
Jan 1, 2014·The Pediatric Infectious Disease Journal·Michimaru HaraTatsuo Nishimura
Jul 6, 2014·Journal of Clinical Virology : the Official Publication of the Pan American Society for Clinical Virology·Vivian LuchsingerCarmen E Larrañaga
Dec 3, 2014·Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology·Riitta TurunenTuomas Jartti

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Methods Mentioned

BETA
PCR

Software Mentioned

R
JMP

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