Clinical and histologic description of ocular anatomy in captive black-tailed prairie dogs (Cynomys ludovicianus)

Veterinary Ophthalmology
Jessica M MeekinsJamie N Henningson

Abstract

To describe the clinical and histologic ocular anatomy of the black-tailed prairie dog (PD). Seventeen captive black-tailed PDs (11 males and six females), ranging in age from approximately 4 months to 4.5 years. Complete ocular examinations, including slit-lamp biomicroscopy, direct and indirect ophthalmoscopy, were performed under isoflurane anesthesia. The globes (n = 2) of one black-tailed PD were harvested immediately after euthanasia and processed after formalin fixation. Staining with hematoxylin-eosin, cytokeratin AE1/AE3, glial fibrillary acidic protein, chromogranin A, claudin-5, smooth muscle actin, and vimentin was performed for light microscopic evaluation. A thick mucinous precorneal tear film was present on the ocular surface. A vestigial nictitating membrane was identified in the medial canthus area. The limbus was heavily pigmented, the iris was a dark homogenous brown, and the pupil was round. Funduscopically, there was no tapetum lucidum, the retinal vascular pattern was holangiotic, and a horizontally elongated optic disk was visualized. The most common ocular abnormalities were acquired eyelid margin defects, present in seven eyes of six black-tailed PDs (35.3%). On histologic examination, the retina was as...Continue Reading

References

Oct 1, 1980·Laboratory Animals·R L Peiffer, P T Johnson
Dec 3, 2008·Veterinary Ophthalmology·Fabiano Montiani-FerreiraRogério R Lange
Apr 4, 2009·The Veterinary Clinics of North America. Exotic Animal Practice·John L HooglandLynda Watson
Dec 14, 2011·Veterinary Pathology·P LabelleA L Labelle
Jun 6, 2013·Veterinary Ophthalmology·Julia Rodriguez-Ramos Fernandez, Richard R Dubielzig

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