Clinical and histopathological characteristics in patients with scarring folliculitis type of acne inversa

Dermato-endocrinology
Lingyi LuQiang Ju

Abstract

Objective : This study was designed to study the clinical and histopathological characteristics of patients with the scarring folliculitis type acne inversa in Chinese population.Methods: A total of 21 patients with acne inversa and 6 controls without known dermatological disease were recruited from outpatient department of dermatology and orthopedic surgery. Two-millimeter punch biopsies were taken from 8 patients with acne inversa and 6 controls, fixed in formalin, embedded in paraffin and stained with haematoxylin and eosin prior to histopathological analysis.Results: There were 12 patients (57.14%) belonging to the scarring folliculitis type presented with double comedones, papules, nodules, depressed scars, and were mainly Hurley stage I (66.67%). Many of the scarring folliculitis type were smokers (58.33%), some had a history of occupational exposure (41.67%) and some were overweight (50%), the mean BMI of which is 25.18±3.16 kg/m2. Histopathological changes such as perifollicular inflammation can be observed in scarring folliculitis type of acne inversa and controls as well. However, epidermal hyperplasia, follicular hyperplasia, sebaceous gland disappearance, destruction of hair follicle and sebaceous gland, collagen hy...Continue Reading

References

Jun 6, 2002·Biomedical and Environmental Sciences : BES·Bei-Fan Zhou, UNKNOWN Cooperative Meta-Analysis Group of the Working Group on Obesity in China
Mar 18, 2011·Experimental Dermatology·Qiang JuChristos C Zouboulis
Aug 14, 2012·Experimental Dermatology·Hessel H van der ZeeErrol P Prens
Oct 26, 2012·The Journal of Investigative Dermatology·Andrew E PinkJonathan N W Barker
Dec 14, 2012·The Journal of Investigative Dermatology·Florence Canoui-PoitrineSylvie Bastuji-Garin
Apr 29, 2014·Clinics in Dermatology·Clio DessiniotiChristina Antoniou
Feb 3, 2015·Journal of the European Academy of Dermatology and Venereology : JEADV·C C ZouboulisG B E Jemec
Jul 4, 2015·Dermatology : International Journal for Clinical and Investigative Dermatology·Christos C ZouboulisGregor B E Jemec
Oct 17, 2015·Journal of the American Academy of Dermatology·Hessel H van der Zee, Gregor B E Jemec

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Citations

Oct 6, 2018·Journal of the European Academy of Dermatology and Venereology : JEADV·A-H R JørgensenH C Ring
Oct 28, 2019·International Journal of Dermatology·Franchesca ChoiNatasha A Mesinkovska

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Methods Mentioned

BETA
biopsies

Software Mentioned

Adobe Photoshop

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