Clinical and imaging features of intracranial arterial aneurysms in the pediatric population

Radiographics : a Review Publication of the Radiological Society of North America, Inc
Gunjan AeronBlaise V Jones

Abstract

Intracranial arterial aneurysms (IAAs) are rare in children. Nevertheless, IAAs account for at least 10%-15% of hemorrhagic strokes during the first 2 decades of life. Traditional vascular risk factors, which are common in the adult population, are generally absent in the pediatric population, engendering distinct modes of IAA pathogenesis. Classification of pediatric IAAs according to the pathogenetic mechanism shows eight distinct categories: idiopathic, traumatic, those due to excessive hemodynamic stress, vasculopathic, infectious, noninfectious inflammatory, oncotic, and familial. Pathogenetic mechanism is the best predictor of the clinical course of the disease, response to treatment, and long-term prognosis. The pathogenetic subtypes of pediatric IAA show characteristic and variably overlapping features. In most cases, IAAs manifesting during the first 2 decades of life are idiopathic. IAAs that are idiopathic, traumatic (second most common type), or due to excessive hemodynamic stresses (third most common type) account for more than 80% of IAAs in the pediatric age group. Most of the remaining pediatric IAAs are the result of congenital cerebral aneurysmal arteriopathies or infection. Multiple IAAs are unusual in young ...Continue Reading

References

Dec 1, 1992·The Journal of Pediatrics·R N HussonP A Pizzo
Sep 1, 1991·Surgical Neurology·S ChakraborttyS Matsumoto
Jun 1, 1983·Journal of Neurosurgery·J R Ostergaard, B Voldby
Aug 1, 1994·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·E C Ventureyra, M J Higgins
Apr 1, 1994·Stroke; a Journal of Cerebral Circulation·W I SchievinkD G Piepgras
Aug 26, 1998·Neurology·T DubrovskyC Wood
Aug 15, 2002·Journal of Child Neurology·Joshua L BonkowskyAndrew T Pavia
Sep 20, 2002·AJR. American Journal of Roentgenology·Athos D PatsalidesNicholas J Patronas
May 29, 2004·Current Opinion in Neurology·David S Younger
Apr 19, 2005·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Pierre LasjauniasAugustin Ozanne
Apr 28, 2005·BMC Medical Genetics·Joseph P BroderickRobert D Brown
May 11, 2005·Surgical Neurology·Judy HuangRafael J Tamargo
Mar 15, 2006·Pediatric Radiology·Elzbieta Jurkiewicz, Sergiusz Jóźwiak
Jun 30, 2006·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·D R BuisW P Vandertop
Aug 4, 2006·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Julie A AkeKristie J Lowry
Dec 5, 2006·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Satoshi TanakaIkuo Kobayashi
Jul 25, 2007·Neuroimaging Clinics of North America·Ronit AgidKarel G Ter Brugge
Oct 8, 2008·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Jiantao LiangFeng Ling
Oct 23, 2008·Pediatric Neurology·Po-Cheng HungAlex M-C Wong
Nov 22, 2008·Stroke; a Journal of Cerebral Circulation·Lori C JordanHeather J Fullerton
Apr 10, 2009·AJNR. American Journal of Neuroradiology·S W HettsV V Halbach
Jun 17, 2010·Molecular Therapy : the Journal of the American Society of Gene Therapy·Joseph W FoleyRobin J Ziegler

❮ Previous
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Citations

Dec 6, 2012·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·K O'BrienT Abruzzo
Oct 16, 2015·Journal of Neuroimaging : Official Journal of the American Society of Neuroimaging·Sergio A VargasArthur B Dublin
Dec 17, 2014·Interventional Neuroradiology : Journal of Peritherapeutic Neuroradiology, Surgical Procedures and Related Neurosciences·Kenji YatomiHajime Arai
May 18, 2016·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Bruno C FloresH Hunt Batjer
Jul 18, 2016·Neuroimaging Clinics of North America·Reade A De LeacyThomas P Naidich
May 11, 2019·Journal of Neurosurgery. Pediatrics·Mehdi ChihiRamazan Jabbarli
Jan 7, 2020·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Nader HejratiJehuda Soleman
Mar 27, 2021·Surgical Neurology International·Samer S HozAktham O Al-Khafaji
Jun 26, 2021·British Journal of Neurosurgery·Christopher Paul MillwardConor Mallucci
Jul 13, 2021·Pediatric Clinics of North America·Alaa Montaser, Edward R Smith

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