Clinical and Imaging Predictors of Surgical Outcome in Multilevel Cervical Ossification of Posterior Longitudinal Ligament: An Analysis of 184 Patients

PloS One
Yifei GuLei Liang

Abstract

To investigate the clinical and imaging predictors of surgical outcomes in patients with ossification of the posterior longitudinal ligament (OPLL). From May 2010 to April 2012, a total of 200 consecutive patients with cervical OPLL were recruited for this study. Of them, 184 patients (130 men and 54 women) who could be tracked for more than 24 months after surgery were finally included for analysis. Their demographic, clinical and radiological data were collected preoperatively. The recovery ratio in terms of JOA score was used to assess the outcome of the patients preoperatively and at 2 years postoperatively. A JOA recovery rate less than 50% was considered a poor outcome. Compared with good outcome group, an older mean age at operation, a longer mean duration of symptoms, a lower mean pre-operativer JOA score, and a higher proportion of diabetics were observed in poor outcome group. Patients in poor outcome group were more likely to present kyphotic cervical alignment, smaller mean transverse area of the spinal cord, and intramedullary signal abnormalities. The result of multivariate stepwise logistic regression showed that a longer duration of symptoms and the presence of T1 hypo-intensity intramedullary changes on MRI wer...Continue Reading

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Citations

Dec 28, 2016·Journal of Orthopaedic Science : Official Journal of the Japanese Orthopaedic Association·Takashi TsujiKen Ishii
Nov 9, 2017·Asian Journal of Neurosurgery·Guruprasad BettaswamySanjay Behari
Jun 3, 2016·Current Reviews in Musculoskeletal Medicine·So Kato, Michael Fehlings
Jun 4, 2018·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·En-Yuan LinHsiao-Yean Chiu
Mar 20, 2018·Frontiers in Neuroscience·Sandra PuentesKenji Suzuki
Oct 23, 2020·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Leixin WeiWen Yuan

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