Abstract
To assess the clinical and microbiological efficacy of chlorine dioxide (ClO2) as a topical antiseptic for the treatment of chronic atrophic candidiasis in geriatric patients. Thirty patients with chronic atrophic candidiasis. Patients were instructed to rinse the mouth with 0.8% ClO2 mouth rinse (DioxiDent) twice daily for one minute and to soak their dentures overnight in the ClO2 for 10 days. Patients were evaluated both clinically and microbiologically at baseline and after 10 days, and any significant side effects were recorded. The clinical appearance of the oral soft tissues was scored on a scale of 0-3 (0 indicating no clinical signs, 1 indicating involvement of < 25% of the palatal mucosa, 2 indicating involvement of 25-50% of the palatal mucosa, and 3 indicating marked erythema involving > 50% of the palatal mucosa). Microbiological testing was undertaken to determine the number of colony forming units (CFUs) of Candida albicans. ClO2 significantly improved the clinical appearance and microbial count (p < 0.001) after treatment, without significant side effects. Results showed marked improvement in the clinical appearance of the tissues after 10 days, with total resolution in the majority of cases. The total CFU/ml ra...Continue Reading
References
Mar 1, 1978·The Journal of the American Dental Association·E Budtz-Jörgensen
May 1, 1989·The Journal of Prosthetic Dentistry·J A BellD A Sackuvich
Apr 1, 1985·Journal of Applied Toxicology : JAT·S E GergesS Von Hagen
Mar 1, 1967·Applied Microbiology·M A BenardeB Davidson
Jun 1, 1983·Journal of Applied Toxicology : JAT·J ScatinaH Alliger
Mar 1, 1984·Southern Medical Journal·B RoduJ P Gockerman
Apr 1, 1983·Journal of Applied Toxicology : JAT·D H SuhR J Bull
Jan 1, 1980·Archives of Oral Biology·T M Arendorf, D M Walker
Jan 1, 1994·Critical Reviews in Oral Biology and Medicine : an Official Publication of the American Association of Oral Biologists·C ScullyL P Samaranayake
Jul 1, 1997·Journal of the American Geriatrics Society·K ShayR P Renner
Apr 2, 1998·Clinical Therapeutics·J B Epstein, B Polsky
Feb 16, 2000·Oral Diseases·D W Williams, M A Lewis
Jun 26, 2001·Journal of Clinical Periodontology·C J SilwoodE Lynch
Aug 16, 2001·Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics·L L PattonD A Shugars
Apr 1, 1997·The Veterinary Quarterly·D N Carlotti
Citations
Mar 16, 2013·Clinical Oral Investigations·Hubert ChangMartin Grootveld
Feb 16, 2010·Trials·Kayoko ShinadaYoko Kawaguchi
Dec 11, 2008·Trials·Kayoko ShinadaYoko Kawaguchi
Oct 13, 2010·Biocontrol Science·Iwao KuroyamaTakahiro Ogawa
Sep 13, 2011·The Journal of Oral Implantology·Iwao KuroyamaTakahiro Ogawa
Mar 5, 2016·Journal of Oral Biology and Craniofacial Research·Sravan Kumar YeturuKalyana Chakravarthy Pentapati
May 11, 2011·Gerodontology·Ufuk IşeriYasemin Kulak Ozkan
Apr 12, 2016·Journal of Prosthodontics : Official Journal of the American College of Prosthodontists·Alexandra YarboroughLisa Stoner
Sep 26, 2013·Acta Microbiologica Et Immunologica Hungarica·Anna HerczeghZsolt Lohinai
Sep 22, 2010·Journal of Applied Oral Science : Revista FOB·Altay UludamarIsmail Ceyhan
Jun 5, 2020·Hospital Practice·Meghana S Karnik-Henry
Jun 16, 2010·Gerodontology·Altay UludamarYasemin Kulak Ozkan