Clinical and microbiological efficacy of chlorine dioxide in the management of chronic atrophic candidiasis: an open study

International Dental Journal
Abdel R MohammadHoward Alliger

Abstract

To assess the clinical and microbiological efficacy of chlorine dioxide (ClO2) as a topical antiseptic for the treatment of chronic atrophic candidiasis in geriatric patients. Thirty patients with chronic atrophic candidiasis. Patients were instructed to rinse the mouth with 0.8% ClO2 mouth rinse (DioxiDent) twice daily for one minute and to soak their dentures overnight in the ClO2 for 10 days. Patients were evaluated both clinically and microbiologically at baseline and after 10 days, and any significant side effects were recorded. The clinical appearance of the oral soft tissues was scored on a scale of 0-3 (0 indicating no clinical signs, 1 indicating involvement of < 25% of the palatal mucosa, 2 indicating involvement of 25-50% of the palatal mucosa, and 3 indicating marked erythema involving > 50% of the palatal mucosa). Microbiological testing was undertaken to determine the number of colony forming units (CFUs) of Candida albicans. ClO2 significantly improved the clinical appearance and microbial count (p < 0.001) after treatment, without significant side effects. Results showed marked improvement in the clinical appearance of the tissues after 10 days, with total resolution in the majority of cases. The total CFU/ml ra...Continue Reading

References

Mar 1, 1978·The Journal of the American Dental Association·E Budtz-Jörgensen
May 1, 1989·The Journal of Prosthetic Dentistry·J A BellD A Sackuvich
Apr 1, 1985·Journal of Applied Toxicology : JAT·S E GergesS Von Hagen
Mar 1, 1967·Applied Microbiology·M A BenardeB Davidson
Jun 1, 1983·Journal of Applied Toxicology : JAT·J ScatinaH Alliger
Mar 1, 1984·Southern Medical Journal·B RoduJ P Gockerman
Apr 1, 1983·Journal of Applied Toxicology : JAT·D H SuhR J Bull
Jan 1, 1980·Archives of Oral Biology·T M Arendorf, D M Walker
Jan 1, 1994·Critical Reviews in Oral Biology and Medicine : an Official Publication of the American Association of Oral Biologists·C ScullyL P Samaranayake
Jul 1, 1997·Journal of the American Geriatrics Society·K ShayR P Renner
Apr 2, 1998·Clinical Therapeutics·J B Epstein, B Polsky
Feb 16, 2000·Oral Diseases·D W Williams, M A Lewis
Aug 16, 2001·Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics·L L PattonD A Shugars
Apr 1, 1997·The Veterinary Quarterly·D N Carlotti

❮ Previous
Next ❯

Citations

Mar 16, 2013·Clinical Oral Investigations·Hubert ChangMartin Grootveld
Sep 13, 2011·The Journal of Oral Implantology·Iwao KuroyamaTakahiro Ogawa
Mar 5, 2016·Journal of Oral Biology and Craniofacial Research·Sravan Kumar YeturuKalyana Chakravarthy Pentapati
Apr 12, 2016·Journal of Prosthodontics : Official Journal of the American College of Prosthodontists·Alexandra YarboroughLisa Stoner
Sep 22, 2010·Journal of Applied Oral Science : Revista FOB·Altay UludamarIsmail Ceyhan

❮ Previous
Next ❯

Related Concepts

Related Feeds

Candidiasis

Candidiasis is a common fungal infection caused by Candida and it can affect many parts for the body including mucosal membranes as well as the gastrointestinal, urinary, and respiratory tracts. Here is the latest research.

Candidiasis (ASM)

Candidiasis is a common fungal infection caused by Candida and it can affect many parts for the body including mucosal membranes as well as the gastrointestinal, urinary, and respiratory tracts. Here is the latest research.

Candida albicans

Candida albicans is an opportunistic, fungal pathogen of humans that frequently causes superficial infections of oral and vaginal mucosal surfaces of debilitated and susceptible individuals. Discover the latest research on Candida albicans here.