PMID: 20624357Jul 14, 2010Paper

Clinical and mycologic characteristics of onychomycosis in diabetic patients

Acta dermatovenerologica Croatica : ADC
Nawaf Al-MutairiDhuha Abdullah Al-Rqobah

Abstract

The aim of the study was to examine the relative prevalence of dermatophytic, yeast and non-dermatophytic mould onychomycosis among diabetic patients, and to compare it with nondiabetic patients. The study included 460 consecutive diabetic patients and the same number of nondiabetic age-matched subjects attending dermatology clinics at Farwaniya Hospital, Kuwait, over a period of 4 years. All patients were examined clinically and mycologically for any evidence of onychomycosis. All cases of clinically suspected and/or mycologically proven onychomycosis were prescribed terbinafine tablets 250 mg orally per day continuously for 6-12 weeks. The prevalence of clinical onychomycosis in the diabetic and control group was 18.7% (86 cases) and 5.7% (26 cases), respectively. Elderly diabetic patients were at an increased risk of developing onychomycosis. Toenails were affected in 54 (62.8%), fingernails in 20 (23.3%), and both fingernails and toenails in 12 (14%) cases in diabetic group. Distal subungual onychomycosis was the most common clinical presentation, recorded in 67.4% of patients, followed by total dystrophic onychomycosis in 11.6% of patients. Culture positivity alone was seen in 16 (18.6%), both culture and KOH positivity in...Continue Reading

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