Abstract
Primary lymphomas of the small intestine (PIL) show definite racial and geographic distribution. Clinical and laboratory data on 132 patients with PIL treated and followed up over a 14-year period in Baghdad, Iraq, are presented. Based on the pattern of involvement of the bowel and the histopathologic appearance of the tumor, the patients can be divided into three main groups. Ninety-seven patients had diffuse lymphoplasmacytic infiltration affecting large segments of the upper bowel. Abdominal pain, anorexia, weight loss, diarrhea, malabsorption, and clubbing of the fingers are the most common clinical findings. The barium appearance of the small intestine and peroral jejunal biopsy specimens are abnormal in nearly all cases. This clinicopathologic entity has been referred to in the literature as Mediterranean lymphoma (ML). Ten of 34 patients tested had free alpha-heavy chain in the serum. Twenty-three cases had other "Western" variants of lymphoma (18 lymphocytic and 5 plasmacytic). The lesions were localized, occurring most frequently in the lower ileum or ileocecal area. The most common presentation was intestinal obstruction. Twelve children had Burkitt's lymphoma (BL), presenting most commonly with abdominal masses and/o...Continue Reading
References
Oct 22, 1977·Lancet·G A Pangalis, H Rappaport
Sep 30, 1978·Lancet·T I Al-Saleem
Jul 1, 1978·Gut·Z Al-BahraniJ King
Mar 1, 1979·Histopathology·T Al-Saleem, I M Zardawi
Jan 15, 1979·International Journal of Cancer. Journal International Du Cancer·A Al-AttarT Al-Saleem
Apr 1, 1978·Cancer·V H NassarS M Nasrallah
Nov 1, 1976·Cancer·S TabbaneN Mourali
Dec 1, 1976·Cancer·K J LewinB H Novis
Dec 1, 1972·Gut·W F DoeC C Booth
Dec 20, 1968·Science·M SeligmannJ L Preud'homme
Feb 1, 1973·Cancer·T al-Saleem, Z al-Bahrani
Aug 1, 1970·Gut·K NasrM Haghshenas
Jun 1, 1972·Cancer·H RappaportJ K Park
Mar 15, 1971·International Journal of Cancer. Journal International Du Cancer·A A BarekatW Dutz
Sep 24, 1981·The New England Journal of Medicine·J L Ziegler
Jan 1, 1982·Reviews of Infectious Diseases·D N CarneyJ D Minna
Nov 1, 1958·The British Journal of Surgery·D BURKITT
Apr 1, 1965·Cancer·D BURKITTD H WRIGHT
May 1, 1972·Postgraduate Medical Journal·S N SalemH Al-Awady
Citations
Jul 15, 1996·Cancer·D L PageW D Dupont
Jan 1, 1992·Diagnostic Cytopathology·A P Dei TosL Bittesini
Jan 1, 1994·Diagnostic Cytopathology·R H BardalesM W Stanley
Nov 1, 1995·Diagnostic Cytopathology·A P Kyriazis, A A Kyriazis
Nov 6, 1993·Lancet·R Menai-Williams
Mar 7, 2000·Journal of the American College of Surgeons·L G KoniarisJ L Cameron
Feb 28, 1991·The New England Journal of Medicine
Oct 31, 1991·The New England Journal of Medicine
Jul 29, 1993·The New England Journal of Medicine
Jul 25, 2006·The American Journal of Surgical Pathology·Laura C CollinsStuart J Schnitt
Aug 13, 2002·European Journal of Gastroenterology & Hepatology·Nicola LeoneMario Rizzetto
Nov 19, 2010·The American Journal of Surgical Pathology·Christine A WynveenEdi Brogi
Jul 1, 1994·Journal of Internal Medicine·E M Mathus-VliegenG N Tytgat
Oct 1, 1990·The American Journal of Medicine·A Khojasteh, P Haghighi
May 1, 1989·European Journal of Cancer & Clinical Oncology·N S el SaghirA E Stuart
Oct 1, 1993·Human Pathology·T al-Saleem
May 1, 1986·American Journal of Hematology·H Al-Mondhiry
Aug 9, 2006·European Journal of Gastroenterology & Hepatology·Ioanna EconomidouTheodora Papadakis
Nov 16, 2004·Blood·Tahseen Al-Saleem, Hamid Al-Mondhiry
Jun 1, 1991·Scottish Medical Journal·C KyriacouR E Mass
Jan 11, 1991·Medical and Pediatric Oncology·C R Thomas, R Share
May 1, 1992·Annals of Saudi Medicine·I A Al-Mofleh
Apr 1, 1985·Pathology·J M Skinner