PMID: 18200412Jan 18, 2008Paper

Clinical and radiographic features of HIV-related pulmonary tuberculosis according to the level of immunosuppression

Revista Da Sociedade Brasileira De Medicina Tropical
Guilherme Freire GarciaManoel Otávio da Costa Rocha

Abstract

Medical charts and radiographs from 38 HIV-infected patients with positive cultures for Mycobacterium tuberculosis from sputum or bronchoalveolar lavage were reviewed in order to compare the clinical, radiographic, and sputum bacilloscopy characteristics of HIV-infected patients with pulmonary tuberculosis according to CD4+ lymphocyte count (CD4). The mean age of the patients was 32 years and 76% were male. The median CD4 was 106 cells/mm(3) and 71% had CD4 < 200 cells/mm(3). Sputum bacilloscopy was positive in 45% of the patients. Patients with CD4 < 200 cells/mm(3) showed significantly less post-primary pattern (7% vs. 63%; p = 0.02) and more frequently reported weight loss (p = 0.04). Although not statistically significant, patients with lower CD4 showed lower positivity of sputum bacilloscopy (37% vs. 64%; p = 0.18). HIV-infected patients with culture-confirmed pulmonary tuberculosis had a high proportion of non-post-primary pattern in thoracic radiographs. Patients with CD4 lower than 200 cells/mm(3) showed post-primary patterns less frequently and reported weight loss more frequently.

References

Jul 1, 1990·The Journal of Infectious Diseases·C P TheuerR E Chaisson
May 1, 1989·The American Review of Respiratory Disease·R L ColebundersH L Francis
Nov 1, 1995·American Journal of Respiratory and Critical Care Medicine·A L PozniakJ Weinberg
Aug 1, 1995·Journal of Medical Microbiology·F A DrobniewskiA H Uttley
Nov 14, 1997·American Journal of Respiratory and Critical Care Medicine·B E JonesP F Barnes
Oct 9, 1998·Transactions of the Royal Society of Tropical Medicine and Hygiene·H T BandaP A Nunn
Mar 2, 1999·American Journal of Respiratory and Critical Care Medicine·J MurrayP Godfrey-Faussett
May 14, 2003·Archives of Internal Medicine·Elizabeth L CorbettChristopher Dye
Mar 26, 2004·Revista Da Sociedade Brasileira De Medicina Tropical·Isabella Ramos de Oliveira LiberatoHeloísa Ramos Lacerda de Melo
Jun 9, 2005·JAMA : the Journal of the American Medical Association·Elvin GengNeil W Schluger

❮ Previous
Next ❯

Citations

Apr 13, 2011·Clinical Microbiology Reviews·Candice K Kwan, Joel D Ernst
Aug 24, 2013·International Journal of STD & AIDS·Yvana Maria Maia de AlbuquerqueVera Magalhães
Apr 9, 2010·Current Opinion in Pulmonary Medicine·Jonathan PeterKeertan Dheda
Jan 14, 2012·Jornal brasileiro de pneumologia : publicaça̋o oficial da Sociedade Brasileira de Pneumologia e Tisilogia·Aline BesenRosemeri Maurici da Silva

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Seminars in Respiratory Infections
William J Burman, Brenda E Jones
The European Respiratory Journal
M SesterEuropean Network for global cooperation in the field of AIDS and TB (EUCO-Net)
Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America
David J HorneMasahiro Narita
© 2021 Meta ULC. All rights reserved