Clinical and Radiological Evaluations of COVID-19 Patients With Anosmia: Preliminary Report

The Laryngoscope
Jerome R Lechiens. saussez

Abstract

To investigate clinical and radiological features of olfactory clefts of patients with mild coronavirus disease 2019 (COVID-19). Prospective non controlled study. Sixteen COVID-19 patients were recruited. The epidemiological and clinical data were extracted. Nasal complaints were assessed through the 22-item Sino-Nasal Outcome Test. Patients underwent psychophysical olfactory testing, olfactory cleft examination, and computed tomography (CT) scans. Sixteen anosmic patients were included. The mean Sniffin' Sticks score was 4.6 ± 1.7. The majority of patients had no endoscopical abnormality, with a mean olfactory cleft endoscopy score of 0.6 ± 0.9. The olfactory clefts were opacified in three patients on the CT scan. The mean radiological olfactory cleft score was 0.7 ± 0.8. There were no significant correlations between clinical, radiological, and psychophysical olfactory testing. The olfactory cleft of anosmic COVID-19 patients is free regarding endoscopic examination and imaging. The anosmia etiology is not related to edema of the olfactory cleft. 4 Laryngoscope, 130:2526-2531, 2020.

References

Mar 3, 1998·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·S C HongS J Zinreich
Oct 6, 2006·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·T HummelA Mackay-Sim
Oct 2, 2014·Clinical Otolaryngology : Official Journal of ENT-UK ; Official Journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery·Clotilde de DorlodotAnne-Lise Poirrier
Jan 1, 2016·International Forum of Allergy & Rhinology·Zachary M SolerRodney J Schlosser
Mar 1, 2018·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Sophia C PolettiThomas Hummel
Jun 22, 2018·Journal of Virology·Mathieu DubéPierre J Talbot
Aug 21, 2019·International Forum of Allergy & Rhinology·Jose L MattosZachary M Soler
Apr 8, 2020·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Jerome R LechienSven Saussez
Apr 17, 2020·Academic Radiology·Mahboobeh Karimi GalougahiSara Haseli
May 6, 2020·Journal of Otolaryngology - Head & Neck Surgery = Le Journal D'oto-rhino-laryngologie Et De Chirurgie Cervico-faciale·Claire HopkinsB Nirmal Kumar
May 14, 2020·Minerva anestesiologica·Gaetano BulfamanteGiovanni Felisati

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Citations

Aug 21, 2020·Head and Neck Pathology·Jerome R LechienSven Saussez
Nov 17, 2020·The Journal of Laryngology and Otology·L A VairaG De Riu
Jan 17, 2021·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Jerome R LechienSven Saussez
Jan 6, 2021·European Journal of Nuclear Medicine and Molecular Imaging·Maxime NiesenXavier De Tiège
Nov 26, 2020·International Forum of Allergy & Rhinology·Richard R OrlandiBing Zhou
May 1, 2021·International Journal of Environmental Research and Public Health·Gabriele MelegariAlberto Barbieri
Jun 7, 2021·Rhinology·M ZugajW J Fokkens
Jul 22, 2021·The Laryngoscope·Luigi Angelo VairaAndrea Fausto Piana
Aug 3, 2021·Lancet Neurology·Michael S XydakisStanley Perlman
Oct 1, 2021·Ear, Nose, & Throat Journal·Xiangming Meng, Yuandan Pan

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