PMID: 7336137Jan 1, 1981Paper

Clinical and subclinical hepatitis A occurring after immunoglobulin prophylaxis among Swedish UN soldiers in Sinai

Scandinavian Journal of Gastroenterology
O WeilandL Tideström

Abstract

This study was performed to investigate the efficiency of 5 ml of 16.5% immunoglobulin (Ig) with an antibody titer against hepatitis A (anti-HAV) of 1:4000, using the HAVAB RIA technique, as pre-infection prophylaxis in 610 Swedish UN soldiers stationed in Sinai for 6 months. Sera were collected from 553 of these soldiers before, during, and after their service and were tested by the HAVAB technique for anti-HAV. Only 13 of 553 (2.4%) were immune before their service. During the first 5 months in Sinai, only one subclinical case of hepatitis A occurred among the men. Thereafter, two subclinical and four clinical cases occurred, although one of the subclinical cases and the four clinical ones did not occur until after the 6-month period. Thus, the Ig prophylaxis scheme used seems to offer almost complete passive protection for 5 months.

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Citations

May 15, 2003·Vaccine·Gloria Taliani, Giovanni Battista Gaeta
Jan 1, 1992·Vaccine·J T Stapleton
May 1, 1993·Journal of Medical Virology·G PapaevangelouA Safary
Jun 12, 2012·World Journal of Virology·Andreas Dotzauer, Leena Kraemer
Apr 17, 2009·The Cochrane Database of Systematic Reviews·Jian Ping LiuYutong Fei
Feb 17, 2001·Journal of Travel Medicine·T Jelinek T, H D Nothdurft

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