Clinical, angiographic, and intravascular ultrasound characteristics of early saphenous vein graft failure

Journal of the American College of Cardiology
Daniel CanosNeil J Weissman

Abstract

We sought to examine saphenous vein graft (SVG) lesions that fail within the first year after operation. Saphenous vein grafts remain patent for approximately 10 years; however, up to 15% to 20% of SVGs become occluded within the first year. We studied 100 patients who underwent percutaneous coronary intervention (PCI) for early (<1 year post-implantation) SVG failure lesions and compared them with a diabetes- and hypercholesterolemia-matched cohort of late SVG failures (>1 year). Coronary angiography and intravascular ultrasound images were analyzed. The majority of patients in both groups were males who presented with unstable angina; 36% were diabetic. Graft ages were 6.0 +/- 2.9 months and 105.4 +/- 50.8 months, respectively. The early SVG failure lesion location was more often ostial or proximal (62% vs. 42%, respectively). Early SVG failures were angiographically smaller than late failures (reference: 2.47 +/- 0.86 mm vs. 3.26 +/- 0.83 mm, p < 0.001) but had similar lesion lengths. Intravascular ultrasound showed that early failure lesions had smaller proximal and distal reference lumen areas (7.3 +/- 6.8 mm2 vs. 10.6 +/- 3.8 mm2, p = 0.026) and greater reference plaque burden than late failures (52.3% vs. 36.1%, p < 0.00...Continue Reading

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Citations

Nov 19, 2013·Revista Portuguesa De Cardiologia : Orgão Oficial Da Sociedade Portuguesa De Cardiologia = Portuguese Journal of Cardiology : an Official Journal of the Portuguese Society of Cardiology·Nuri Ilker AkkusMehmet Cilingiroglu
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May 25, 2016·Cardiovascular Revascularization Medicine : Including Molecular Interventions·Roberto ScarsiniFlavio L Ribichini
Sep 30, 2016·Cardiovascular Intervention and Therapeutics·Eiji IchimotoMizuo Nameki
Aug 19, 2016·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Barbara A DanekEmmanouil Brilakis
Aug 28, 2009·Critical Reviews in Biotechnology·Pardeep Kumar, T Satyanarayana
Dec 19, 2014·JAAPA : Official Journal of the American Academy of Physician Assistants·Andrew R Wyant, DeShana Collett

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