Abstract
We sought to examine saphenous vein graft (SVG) lesions that fail within the first year after operation. Saphenous vein grafts remain patent for approximately 10 years; however, up to 15% to 20% of SVGs become occluded within the first year. We studied 100 patients who underwent percutaneous coronary intervention (PCI) for early (<1 year post-implantation) SVG failure lesions and compared them with a diabetes- and hypercholesterolemia-matched cohort of late SVG failures (>1 year). Coronary angiography and intravascular ultrasound images were analyzed. The majority of patients in both groups were males who presented with unstable angina; 36% were diabetic. Graft ages were 6.0 +/- 2.9 months and 105.4 +/- 50.8 months, respectively. The early SVG failure lesion location was more often ostial or proximal (62% vs. 42%, respectively). Early SVG failures were angiographically smaller than late failures (reference: 2.47 +/- 0.86 mm vs. 3.26 +/- 0.83 mm, p < 0.001) but had similar lesion lengths. Intravascular ultrasound showed that early failure lesions had smaller proximal and distal reference lumen areas (7.3 +/- 6.8 mm2 vs. 10.6 +/- 3.8 mm2, p = 0.026) and greater reference plaque burden than late failures (52.3% vs. 36.1%, p < 0.00...Continue Reading
References
Dec 11, 1976·The American Journal of Cardiology·G M LawrieH L Beazley
Apr 1, 1991·Journal of the American College of Cardiology·M G Bourassa
Nov 22, 1984·The New England Journal of Medicine·L CampeauA Sniderman
Nov 15, 1995·The American Journal of Cardiology·F O MendelsohnN J Weissman
Apr 1, 1995·Journal of the American College of Cardiology·K B DavisJ W Kennedy
Aug 27, 1994·Lancet·S YusufR Norris
Feb 15, 1996·Circulation·T NishiokaR J Siegel
Sep 11, 1997·The New England Journal of Medicine·M P SavageS Goldberg
Apr 1, 1998·Circulation·J G Motwani, E J Topol
Mar 18, 1999·The American Journal of Cardiology·M R Le MayL A Higginson
Nov 24, 1999·The American Journal of Cardiology·M K HongM B Leon
May 12, 2000·Journal of the American College of Cardiology·J M AhmedM B Leon
Apr 13, 2001·Journal of the American College of Cardiology·G S MintzP G Yock
Citations
Nov 19, 2013·Revista Portuguesa De Cardiologia : Orgão Oficial Da Sociedade Portuguesa De Cardiologia = Portuguese Journal of Cardiology : an Official Journal of the Portuguese Society of Cardiology·Nuri Ilker AkkusMehmet Cilingiroglu
May 21, 2009·American Journal of Therapeutics·Matthew D BacchettaDaniel F Catanzaro
Oct 15, 2011·The Annals of Thoracic Surgery·Soroosh KianiRobert S Poston
Aug 3, 2010·Atherosclerosis·Frances O WoodEmmanouil S Brilakis
Feb 24, 2007·The American Journal of Cardiology·William Joseph van GaalDaniel James Blackman
Apr 29, 2008·Journal of Vascular Surgery·Christopher D OwensMichael S Conte
May 9, 2006·The American Journal of Cardiology·Koichi SanoMartin B Leon
Oct 29, 2005·The American Journal of Cardiology·Abdul R HalabiPeter K Smith
Oct 20, 2009·Journal of Vascular Surgery·Christopher D Owens
Jun 21, 2005·Journal of the American College of Cardiology·Jerzy PregowskiNeil J Weissman
Feb 7, 2006·Journal of the American College of Cardiology·C Noel Bairey MerzUNKNOWN WISE Investigators
Jun 28, 2011·JACC. Cardiovascular Interventions·Periklis DavlourosDimitrios Alexopoulos
May 25, 2016·Cardiovascular Revascularization Medicine : Including Molecular Interventions·Roberto ScarsiniFlavio L Ribichini
Sep 30, 2016·Cardiovascular Intervention and Therapeutics·Eiji IchimotoMizuo Nameki
Aug 19, 2016·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Barbara A DanekEmmanouil Brilakis
Jun 26, 2014·Perfusion·A MominJ Desai
Aug 28, 2009·Critical Reviews in Biotechnology·Pardeep Kumar, T Satyanarayana
Dec 19, 2014·JAAPA : Official Journal of the American Academy of Physician Assistants·Andrew R Wyant, DeShana Collett
Jan 31, 2021·Cardiology and Therapy·Brian McNicholsKi Park
Jul 6, 2006·Circulation·George T LauLeonard Kritharides