Clinical application of a novel hybrid intensity-modulated radiotherapy technique for stage III lung cancer and dosimetric comparison with four other techniques

International Journal of Radiation Oncology, Biology, Physics
Wilko F A R VerbakelSuresh Senan

Abstract

In large stage III lung tumors, planning delivery of doses exceeding 60 Gy can be challenging and time consuming. Intensity modulated radiation therapy (IMRT) can improve target coverage but may increase volumes receiving low-dose irradiation. We clinically implemented a novel hybrid IMRT (h-IMRT) technique that allowed plans to be produced quickly, and compared these plans with 4 other techniques. h-IMRT was used to treat 14 consecutive patients with planning target volumes (PTVs) exceeding 500 cm(3) (average, 779 cm(3)) with concurrent chemo-radiation therapy to 66 Gy. h-IMRT plans consisted of 2 components: an anterior-posterior/posterior-anterior/posterior-anterior (AP-PA-PA) oblique, open-field technique delivering an average dose of 58 Gy, plus a 3-field IMRT component optimized to achieve a final homogeneous dose of 66 Gy. Total lung V(20) and contralateral lung V(5) were kept as low as possible but preferably less than 35% and less than 50%, respectively. All plans were retrospectively replanned using a 5- to 9-field 3-dimensional conformal technique, full RapidArc, 6-field full IMRT, and a hybrid RapidArc (h-RapidArc) technique similar to the h-IMRT. The h-IMRT, h-RapidArc, and full RapidArc plans could be generated in...Continue Reading

References

Sep 16, 1999·International Journal of Radiation Oncology, Biology, Physics·M V GrahamC A Perez
Apr 13, 2000·International Journal of Radiation Oncology, Biology, Physics·M L DirkxB J Heijmen
May 13, 2006·International Journal of Radiation Oncology, Biology, Physics·H Helen LiuRadhe Mohan
Jun 6, 2006·International Journal of Radiation Oncology, Biology, Physics·Aaron M AllenElizabeth H Baldini
Feb 12, 2008·International Journal of Radiation Oncology, Biology, Physics·Charles S MayoMadeleine Bogdanov
Oct 28, 2008·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Jim RoseDavid D'Souza
Mar 9, 2010·International Journal of Radiation Oncology, Biology, Physics·Chang Hoon SongKwan Ho Cho
Mar 31, 2010·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Anne AupérinJean-Pierre Pignon
Jul 3, 2010·Annals of Oncology : Official Journal of the European Society for Medical Oncology·E C J PhernambucqS Senan
Jul 16, 2010·International Journal of Radiation Oncology, Biology, Physics·ChinLoon OngSuresh Senan
Nov 16, 2010·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Chin Loon OngSuresh Senan
Nov 17, 2010·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Dirk De RuysscherSuresh Senan

❮ Previous
Next ❯

Citations

Jan 18, 2014·Lung Cancer : Journal of the International Association for the Study of Lung Cancer·Gwendolyn H M J GriffioenSuresh Senan
Oct 8, 2013·Medical Dosimetry : Official Journal of the American Association of Medical Dosimetrists·John Agapito
Mar 5, 2013·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Sashendra SenthiSuresh Senan
Jun 23, 2015·Critical Reviews in Oncology/hematology·Benoite MéryNicolas Magné
Sep 16, 2014·Cancer radiothérapie : journal de la Société française de radiothérapie oncologique·M AyadiF Mornex
Sep 26, 2013·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Max Dahele, Suresh Senan
Jan 30, 2013·Lung Cancer : Journal of the International Association for the Study of Lung Cancer·Terry G WiersmaSuresh Senan
Jun 24, 2015·Journal of Applied Clinical Medical Physics·Marloes JeulinkWilko F A R Verbakel
Sep 30, 2016·Technology in Cancer Research & Treatment·Scott R SilvaMehee Choi
Jun 29, 2017·Journal of Applied Clinical Medical Physics·Weijie LeiLiqin Hu
Jun 18, 2017·Physica Medica : PM : an International Journal Devoted to the Applications of Physics to Medicine and Biology : Official Journal of the Italian Association of Biomedical Physics (AIFB)·Sitaraman BalajiSubramanianSumana Premkumar
Mar 15, 2019·Asia-Pacific Journal of Clinical Oncology·Phillip ParenteEmily Stone
May 8, 2019·Indian Journal of Cancer·Benoite MeryNicolas Magné

❮ Previous
Next ❯

Related Concepts

Related Feeds

Aphasia

Aphasia affects the ability to process language, including formulation and comprehension of language and speech, as well as the ability to read or write. Here is the latest research on aphasia.

Related Papers

Medical Dosimetry : Official Journal of the American Association of Medical Dosimetrists
Ingrid de BreeLieneke R van Veelen
Cancer radiothérapie : journal de la Société française de radiothérapie oncologique
D RousseauA Paumier
Cancer radiothérapie : journal de la Société française de radiothérapie oncologique
B DubrayR Apardian
© 2021 Meta ULC. All rights reserved