PMID: 15250223Jul 15, 2004Paper

Clinical application of a simple questionnaire for the differentiation of asthma and chronic obstructive pulmonary disease

Respiratory Medicine
Kai Michael BeehRoland Buhl

Abstract

Asthma and chronic obstructive pulmonary disease (COPD) are highly prevalent chronic diseases characterized by airflow limitation. Both diseases have a distinct pathogenesis and require unique treatment approaches. Due to some common characteristic traits, asthma and COPD are often lumped together in clinical practice. We sought to develop a simple questionnaire for the distinction of asthma and COPD. Clinical discriminants of asthma and COPD were retrospectively identified by multiple logistic regression using files from 547 consecutive adult patients presenting to a pulmonary specialist practice with a diagnosis of asthma or COPD. With these features, we generated a simple quantitative questionnaire supporting a diagnosis of COPD with high scores and asthma with low scores (range 0-15 points). Questionnaire results were compared with physician's diagnosis based on GINA and GOLD guidelines including skin tests, spirometry and reversibility data. 210 patients had COPD and 337 had asthma. Age of onset, smoking history, atopy status, and cough quality were significantly associated with a diagnosis of asthma or COPD. Questionnaire scores for COPD patients were higher than those for asthmatics (mean score 10.5+/-0.18 vs. 4+/-0.12, ...Continue Reading

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Citations

May 2, 2014·Molecular Diagnosis & Therapy·Andrea SegretiMario Cazzola
Apr 7, 2010·International Journal of Chronic Obstructive Pulmonary Disease·Barbara P YawnUNKNOWN Lung Function Questionnaire Working Group
Aug 18, 2010·International Journal of Chronic Obstructive Pulmonary Disease·José Luis IzquierdoAlexandra Paravisini
Nov 29, 2011·Journal of Allergy·Amir A ZekiSamuel Louie
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Jul 14, 2010·The American Journal of the Medical Sciences·Antonio Anzueto
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Apr 17, 2009·The Journal of Allergy and Clinical Immunology·Philippe-Jean BousquetJean Bousquet
Apr 1, 2015·Respirology : Official Journal of the Asian Pacific Society of Respirology·Young Seok LeeYeon-Mok Oh
Mar 17, 2007·Respiratory Medicine·Mario CazzolaNicola A Hanania
May 4, 2016·Expert Review of Respiratory Medicine·Nicolas Roche
Apr 24, 2012·The British Journal of General Practice : the Journal of the Royal College of General Practitioners·Marc MiravitllesEsther Anton
Dec 7, 2005·Respiration; International Review of Thoracic Diseases·David G TinkelmanConstant P van Schayck
Jul 3, 2020·Tuberculosis and Respiratory Diseases·Seong AhnYu-Il Kim

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