Clinical application of immunosuppressive agents in renal transplantation

The Surgical Clinics of North America
M R First

Abstract

The availability of a number of new immunosuppressive drugs has resulted in significant improvements in the outcome of kidney transplantation. Currently 1-year graft survival rate for cadaver kidney transplants is approximately 85%. A number of new agents are presently in clinical studies. This article reviews the currently available agents and examines various aspects of induction and maintenance immunosuppressive therapy, and the treatment of acute rejection episodes. In addition, the agents currently in clinical trials and future directions in immunosuppressive therapy are discussed.

Citations

May 30, 2001·Transplantation Proceedings·M R First
Sep 25, 2002·Transplantation Proceedings·A StephanA M Masri
Mar 20, 1999·Transplantation Proceedings·M R First
Jun 29, 2001·Transplant Infectious Disease : an Official Journal of the Transplantation Society·R CoralesR K Avery
Apr 20, 2002·Current Opinion in Infectious Diseases·Melanie W PoundJohn R Perfect
Jan 15, 1999·The Journal of Cardiovascular Nursing·H M Schell
May 24, 2000·Clinical Therapeutics·K JonesD W Holt
Jan 11, 2000·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·J LindbergS Fishbane

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