Clinical application of indocyanine green (ICG) fluorescent imaging of hepatoblastoma

Journal of Pediatric Surgery
Taku YamamichiNoriaki Usui

Abstract

Although the usefulness of intraoperative indocyanine green (ICG) fluorescent imaging for the resection of hepatocellular carcinoma has been reported, its usefulness for the resection of hepatoblastoma remains unclear. This study clarifies the feasibility of intraoperative ICG fluorescent imaging for the resection of hepatoblastoma. In three hepatoblastoma patients, a primary tumor, recurrent tumor, and lung metastatic lesions were intraoperatively examined using a near-infrared fluorescence imaging system after the preoperative administration of ICG. ICG fluorescent imaging was useful for the surgical navigation in hepatoblastoma patients. In the first case, the primary hepatoblastoma exhibited intense fluorescence during right hepatectomy, but no fluorescence was detected in the residual liver. In the second case, a recurrent tumor exhibited fluorescence between the residual liver and diaphragm. A complete resection of the residual liver, with a partial resection of the diaphragm, followed by liver transplantation was performed. In the third case with multiple lung metastases, each metastatic lesion showed positive fluorescence, and all were completely resected. These fluorescence-positive lesions were pathologically proven t...Continue Reading

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Citations

Dec 27, 2016·Photodiagnosis and Photodynamic Therapy·Ali MajlesaraArianeb Mehrabi
Jun 16, 2018·Journal of Laparoendoscopic & Advanced Surgical Techniques. Part a·Yohei YamadaTatsuo Kuroda
Mar 17, 2017·Journal of Biomedical Optics·Dimitris GorpasVasilis Ntziachristos
Jan 6, 2018·Surgical Innovation·Eva LietoAnnamaria Auricchio
Dec 24, 2018·Children·Irene Isabel P LimGregory M Tiao
Aug 18, 2020·Experimental and Clinical Transplantation : Official Journal of the Middle East Society for Organ Transplantation·Yuta HirataNaohiro Sata
Jun 28, 2019·Pediatric Surgery International·C T LauK K Y Wong
Aug 23, 2019·Cancers·Yohei YamadaTomoro Hishiki
Feb 20, 2019·Pediatric Surgery International·Ryota SouzakiTomoaki Taguchi
Dec 11, 2019·Cancers·Tianyou YangSanjeev A Vasudevan
May 29, 2020·The Journal of Pediatric Pharmacology and Therapeutics : JPPT : the Official Journal of PPAG·Shabana Zainab ShafyJoseph D Tobias
Oct 20, 2017·Interactive Cardiovascular and Thoracic Surgery·Toyofumi F Chen-YoshikawaHiroshi Date
Oct 27, 2020·European Journal of Pediatric Surgery Reports·Isabel Bada-BoschJuan de Agustin
Mar 13, 2021·Surgical Oncology Clinics of North America·Jonathan Karpelowksy, Guido Seitz
Apr 10, 2021·Journal of Vascular Surgery. Venous and Lymphatic Disorders·Yu Jeong ChoJung-Man Namgoong
Sep 10, 2020·Journal of Pediatric Surgery·Irene ParaboschiStefano Giuliani
Dec 23, 2020·Annals of Surgery·Xiaoying WangNorihiro Kokudo
May 30, 2021·Journal of Pediatric Surgery·Richard S WhitlockSanjeev A Vasudevan

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