Clinical application of invalid foods using mealworms and evaluation of nutrition status and immune function: a study protocol for a randomized, double blind, placebo-controlled trial

BMC Nutrition
Hyung Sun KimJoon Seong Park

Abstract

Protein intake is important for the recovery of the immune system, physical strength, and wound healing after surgery. Sarcopenia is associated with a poor prognosis when compared to patients without sarcopenia in cancer patients. Recently, edible insects, such as mealworms, have been recognized as having a high protein content. In this study, we will evaluate the effect of nutritional status and immune function change based on a patient's ingestion of mealworms after hepatobiliary pancreatic surgery. This is a prospective, two-armed, phase III study investigating the effect of mealworm improving nutrition and immune status in patients after hepatobiliary pancreatic surgery. In the trial group, the patients will be provided with mealworms for 2 months after surgery. In the control group, patients will be provided with grain powder for 2 months after surgery. The target for accrual is 168 patients. We divided in to three groups according to the type of surgery. The primary endpoint is to evaluate body cell mass index 2 months postoperatively. Secondary endpoints include other body composition changes as well as nutrition index and immune function change. We expect that ingestion of mealworms can effectively improve the nutrition...Continue Reading

Associated Clinical Trials

References

Mar 1, 1996·JPEN. Journal of Parenteral and Enteral Nutrition·A O OlinO Ljungqvist
Jun 8, 1999·JAMA : the Journal of the American Medical Association·D H SullivanR C Walls
Jul 25, 2000·Nutrition·S P Allison
Dec 7, 2002·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·J KondrupN Lauesen
Dec 7, 2007·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·Kristina NormanMatthias Pirlich
Aug 25, 2011·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·Ekta AgarwalElisabeth Isenring
Jan 8, 2015·Critical Care : the Official Journal of the Critical Care Forum·Peter J M WeijsRobert R Wolfe
Oct 22, 2015·Journal of Surgical Oncology·Jeroen L A van VugtJan N M IJzermans

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Citations

Feb 7, 2021·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Joung-Hee KimKeuk-Jun Kim

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Methods Mentioned

BETA
pancreatectomy

Clinical Trials Mentioned

NCT03201926

Software Mentioned

Excel
SPSS

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