Clinical application of MOSkin dosimeters to rectal wall in vivo dosimetry in gynecological HDR brachytherapy

Physica Medica : PM : an International Journal Devoted to the Applications of Physics to Medicine and Biology : Official Journal of the Italian Association of Biomedical Physics (AIFB)
M CarraraAnatoly B Rosenfeld

Abstract

Three MOSkins dosimeters were assembled over a rectal probe and used to perform in vivo dosimetry during HDR brachytherapy treatments of vaginal cancer. The purpose of this study was to verify the applicability of the developed tool to evaluate discrepancies between planned and measured doses to the rectal wall. MOSkin dosimeters from the Centre for Medical Radiation Physics are particularly suitable for brachytherapy procedures for their ability to be easily incorporated into treatment instrumentation. In this study, 26 treatment sessions of HDR vaginal brachytherapy were monitored using three MOSkin mounted on a rectal probe. A total of 78 measurements were collected and compared to doses determined by the treatment planning system. Mean dose discrepancy was determined as 2.2±6.9%, with 44.6% of the measurements within ±5%, 89.2% within ±10% and 10.8% higher than ±10%. When dose discrepancies were grouped according to the time elapsed between imaging and treatment (i.e., group 1: ≤90min; group 2: >90min), mean discrepancies resulted in 4.7±3.6% and 7.1±5.0% for groups 1 and 2, respectively. Furthermore, the position of the dosimeter on the rectal catheter was found to affect uncertainty, where highest uncertainties were obser...Continue Reading

References

Feb 25, 2009·Medical Physics·I S KwanV L Perevertaylo
Mar 3, 2009·International Journal of Radiation Oncology, Biology, Physics·Sylvia Van DykDavid Bernshaw
Mar 7, 2013·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Clare AndersonPeter J Hoskin
Jul 3, 2013·Applied Radiation and Isotopes : Including Data, Instrumentation and Methods for Use in Agriculture, Industry and Medicine·G GambariniA Rosenfeld
Dec 5, 2013·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Christian KirisitsFrank-André Siebert
Jul 10, 2014·The British Journal of Radiology·G KertzscherJ E Cygler
Aug 5, 2014·Physica Medica : PM : an International Journal Devoted to the Applications of Physics to Medicine and Biology : Official Journal of the Italian Association of Biomedical Physics (AIFB)·Z K ZamanK H Ng
Jan 23, 2016·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Mauro CarraraEmanuele Pignoli
Aug 10, 2016·Journal of Contemporary Brachytherapy·Primoz Petric, Christian Kirisits
Sep 15, 2016·Physica Medica : PM : an International Journal Devoted to the Applications of Physics to Medicine and Biology : Official Journal of the Italian Association of Biomedical Physics (AIFB)·Alexander F I OsmanWamied Abdel Rahman
Nov 16, 2016·Physica Medica : PM : an International Journal Devoted to the Applications of Physics to Medicine and Biology : Official Journal of the Italian Association of Biomedical Physics (AIFB)·W L JongG F Ho
Jan 17, 2017·Physica Medica : PM : an International Journal Devoted to the Applications of Physics to Medicine and Biology : Official Journal of the Italian Association of Biomedical Physics (AIFB)·Wei Loong JongJeannie Hsiu Ding Wong

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Citations

Oct 28, 2019·Australasian Physical & Engineering Sciences in Medicine·Z JamalludinN M Ung
Jan 22, 2021·Medical Physics·Sree Bash Chandra DebnathJulien Darreon
Mar 25, 2021·Medical Physics·Hiroaki HayashiTakuya Hashizume
Jul 24, 2021·Biomedical Physics & Engineering Express·Philip C SomerwilNick J van de Berg

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