Clinical applications of 3-dimensional printing in radiation therapy

Medical Dosimetry : Official Journal of the American Association of Medical Dosimetrists
Yizhou ZhaoJames L Robar

Abstract

Three-dimensional (3D) printing is suitable for the fabrication of complex radiotherapy bolus. Although investigated from dosimetric and feasibility standpoints, there are few reports to date of its use for actual patient treatment. This study illustrates the versatile applications of 3D printing in clinical radiation oncology through a selection of patient cases, namely, to create bolus for photon and modulated electron radiotherapy (MERT), as well as applicators for surface high-dose rate (HDR) brachytherapy. Photon boluses were 3D-printed to treat a recurrent squamous cell carcinoma (SCC) of the nasal septum and a basal cell carcinoma (BCC) of the posterior pinna. For a patient with a mycosis fungoides involving the upper face, a 3D-printed MERT bolus was used. To treat an SCC of the nose, a 3D-printed applicator for surface brachytherapy was made. The structures' fit to the anatomy and the radiotherapy treatment plans were assessed. Based on the treatment planning computed tomography (CT), the size of the largest air gap at the interface of the 3D-printed structure was 3 mm for the SCC of the nasal septum, 3 mm for the BCC of the pinna, 2 mm for the mycosis fungoides of the face, and 2 mm for the SCC of the nose. Acceptable...Continue Reading

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Citations

Mar 15, 2018·Current Opinion in Ophthalmology·David Reichstein, Kayla Karan
Sep 29, 2019·Physics in Medicine and Biology·R TinoT Kron
May 28, 2020·Journal of Applied Clinical Medical Physics·Michael K RooneyDaniel W Golden
Jun 12, 2020·Physical and Engineering Sciences in Medicine·S K MaxwellS B Crowe
Feb 6, 2020·Journal of Medical Radiation Sciences·Christine AlbantowChristopher Halsall
Aug 28, 2019·Journal of Applied Clinical Medical Physics·David Kiyoshi SasakiArbind Dubey
Jul 1, 2020·3D Printing in Medicine·Ergys SubashiOana Craciunescu
Jul 6, 2020·Journal of Medical Imaging and Radiation Sciences·Suzzette Renee Spencer, Lynette Kay Watts
Apr 13, 2021·Physical and Engineering Sciences in Medicine·Corey A BridgerAlexandre M Caraça Santos
Oct 29, 2021·Physics in Medicine and Biology·William Y SongXun Jia

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