Clinical applications of QT/RR hysteresis assessment: A systematic review

Annals of Noninvasive Electrocardiology : the Official Journal of the International Society for Holter and Noninvasive Electrocardiology, Inc
Hugo GravelDaniel Curnier

Abstract

QT/RR hysteresis (QT-hys) is an index of the time accommodation of ventricular repolarization to heart rate changes. This report comprehensively reviews studies addressing QT-hys as a biomarker of medical conditions. This is a secondary analysis of data from a recent systematic review pertaining to methods of assessment of QT-hys. Articles included in the former review were filtered in order to select original articles investigating the association of QT-hys with medical conditions in humans. Nineteen articles fulfilled our inclusion criteria. Given the heterogeneity of the methods and investigated conditions, no pooled analysis of data could be implemented. QT-hys was mostly studied as a risk marker of severe arrhythmias, as a predictor of the long QT syndrome (LQTS) phenotypes and genotypes and as a marker of exercise-induced ischemia. An increased QT-hys appears to be implicated in arrhythmogenesis, although the evidence in this regard relies on few human studies. An augmented QT-hys was reported in the LQTS, predominantly in the LQT2 genotype, but conflicting results were obtained between studies using different methods of assessment. In addition, QT-hys appears to be a useful marker of stress-induced myocardial ischemia in...Continue Reading

References

May 1, 1987·Pacing and Clinical Electrophysiology : PACE·J S SarmaU Gadgil
Jun 1, 1955·Archives internationales de physiologie et de biochimie·E CARMELIET
Jan 13, 2004·Journal of Electrocardiology·Esther PueyoMarek Malik
Oct 30, 2004·Pacing and Clinical Electrophysiology : PACE·Vijay S ChauhanRaymond Yee
Jun 17, 2006·Journal of Electrocardiology·Michael S LauerJoseph M Starobin
Nov 13, 2007·Journal of Electrocardiology·Joseph G Akar, Fadi G Akar
Nov 13, 2007·Journal of Electrocardiology·Joseph M StarobinTimothy A Johnson
Jul 5, 2008·American Journal of Physiology. Heart and Circulatory Physiology·Mathias BaumertEugene Nalivaiko
Oct 14, 2008·American Journal of Physiology. Heart and Circulatory Physiology·Marek MalikGeorg Schmidt
Oct 28, 2008·Philosophical Transactions. Series A, Mathematical, Physical, and Engineering Sciences·Esther PueyoPablo Laguna
Jan 15, 2010·Circulation. Arrhythmia and Electrophysiology·Jorge A WongAndrew D Krahn
Mar 9, 2010·American Journal of Physiology. Heart and Circulatory Physiology·Esther PueyoBlanca Rodríguez
Mar 13, 2010·Hypertension Research : Official Journal of the Japanese Society of Hypertension·Mathias BaumertAndreas Voss
Mar 17, 2010·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Ishvinder S ChatthaAndrew D Krahn
Jul 14, 2010·Journal of Interventional Cardiac Electrophysiology : an International Journal of Arrhythmias and Pacing·Josef HalámekSamuel J Asirvatham
Jan 22, 2011·Annals of Noninvasive Electrocardiology : the Official Journal of the International Society for Holter and Noninvasive Electrocardiology, Inc·Jean-Philippe CoudercWojciech Zareba
Apr 16, 2011·Physiological Measurement·Vincent JacquemetTeresa Kuś
May 1, 2012·American Journal of Physiology. Heart and Circulatory Physiology·Daniel J PelchovitzJeffrey J Goldberger
Oct 26, 2012·Annals of Noninvasive Electrocardiology : the Official Journal of the International Society for Holter and Noninvasive Electrocardiology, Inc·Josef HalamekPavel Leinveber
Oct 29, 2013·American Journal of Physiology. Heart and Circulatory Physiology·Marek MalikE Marcel van Gelderen
May 13, 2014·Methods of Information in Medicine·A Bueno-OrovioB Rodriguez
Oct 15, 2014·Circulation Journal : Official Journal of the Japanese Circulation Society·Yijie ZhangTuantuan Tan
Sep 5, 2015·Journal of Electrocardiology·Cees A Swenne
Feb 4, 2016·World Journal of Cardiology·Francesco MonitilloMassimo Iacoviello
May 17, 2017·Annals of Noninvasive Electrocardiology : the Official Journal of the International Society for Holter and Noninvasive Electrocardiology, Inc·Hugo GravelVincent Jacquemet

❮ Previous
Next ❯

Citations

Jun 7, 2018·Journal of Clinical Pharmacology·Marek Malik
Nov 25, 2019·Annals of Noninvasive Electrocardiology : the Official Journal of the International Society for Holter and Noninvasive Electrocardiology, Inc·Katerina Hnatkova, Marek Malik
Sep 27, 2018·Drug Safety : an International Journal of Medical Toxicology and Drug Experience·Marek MalikNorman Stockbridge
Jul 6, 2019·Frontiers in Physiology·Katerina HnatkovaMarek Malik
Feb 15, 2020·Scientific Reports·Ondřej TomanMarek Malik
Aug 21, 2019·Frontiers in Physiology·Irena AndršováMarek Malik
Oct 23, 2019·Scientific Reports·Katerina HnatkovaMarek Malik
Dec 29, 2019·Scientific Reports·Katerina HnatkovaMarek Malik
May 29, 2018·Cardiology Research and Practice·Hirmand NouraeiSimon Rabkin
Sep 27, 2018·Drug Safety : an International Journal of Medical Toxicology and Drug Experience·Marek MalikNorman Stockbridge
Jan 2, 2021·Frontiers in Physiology·Irena AndršováMarek Malik
Feb 24, 2021·Scientific Reports·Katerina HnatkovaMarek Malik
Jul 14, 2021·Scientific Reports·Irena AndršováMarek Malik

❮ Previous
Next ❯

Related Concepts

Related Feeds

Atrial Fibrillation

Atrial fibrillation is a common arrhythmia that is associated with substantial morbidity and mortality, particularly due to stroke and thromboembolism. Here is the latest research.

Arrhythmia

Arrhythmias are abnormalities in heart rhythms, which can be either too fast or too slow. They can result from abnormalities of the initiation of an impulse or impulse conduction or a combination of both. Here is the latest research on arrhythmias.

Related Papers

Annals of Noninvasive Electrocardiology : the Official Journal of the International Society for Holter and Noninvasive Electrocardiology, Inc
Hugo GravelVincent Jacquemet
Journal of Electrocardiology
Marek Malik
Journal of Pharmacokinetics and Pharmacodynamics
Marek MalikNorman Stockbridge
American Journal of Physiology. Heart and Circulatory Physiology
Marek MalikE Marcel van Gelderen
© 2022 Meta ULC. All rights reserved