PMID: 6162928Jan 1, 1981Paper

Clinical aspects of spontaneous necrosis of pituitary tumors (pituitary apoplexy)

Journal of Neurology
A Müller-Jensen, D Lüdecke

Abstract

Among 586 surgically treated tumors of the pituitary gland 72 cases (12.3%) of spontaneous necrosis of the tumor were found. However only in 10 cases (1.7%) were there clues of an additional rupture of the tumor with signs of meningeal reaction in the CSF. Cases with a relatively benign clinical course and signs of regression are more frequent than generally assumed. Spontaneous necrosis with and without rupture is much more frequent in endocrinologically inactive tumors (including prolactinomas) as opposed to STH- and ACTH-cell adenomas. Analyzing the patient material the clinical symptomatology and the differential diagnosis of spontaneous necrosis of the tumor with and without rupture are discussed.

References

Sep 1, 1974·Archives of Internal Medicine·J D JacobiR B Daroff
Sep 1, 1972·Journal of Neurosurgery·R L Rovit, J M Fein

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Citations

May 24, 2003·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·Shinji FukuiHidetoshi Ooigawa
Sep 15, 2012·Neurologia Medico-chirurgica·Kota KurisuKiyohiro Houkin
Dec 13, 2003·Journal of Endocrinological Investigation·M ValenteF Santeusanio
Jan 26, 2010·Neuro-Chirurgie·R MaroufR Glikstein
Oct 31, 2006·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·Kiarash ShahlaieJoe C Watson
Oct 13, 2000·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·S AlatakisG C Fabinyi
Jan 11, 2005·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·G D Satyarthee, A K Mahapatra
Nov 21, 1998·Human Pathology·B K Kleinschmidt-DeMasters, K O Lillehei
Jan 1, 1991·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·P LunardiB Fraioli
May 28, 2004·Expert Opinion on Pharmacotherapy·Philippe ChansonDenis Ducreux
Sep 29, 2015·Endocrine Reviews·Claire BrietPhilippe Chanson
Oct 1, 1986·Acta Neurologica Scandinavica·P Bjerre, J Lindholm
Oct 3, 2001·Physiological Reviews·S C Gandevia
Jan 25, 2020·Hospital Practice·Chun ChuHussam A Yacoub

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