Clinical assessment of retronasal olfactory function

Archives of Otolaryngology--head & Neck Surgery
Stefan HeilmannT Hummel

Abstract

To develop a test kit for the simple assessment of retronasal olfactory function and to compare orthonasal and retronasal olfactory function in healthy subjects and patients with olfactory disorders. We tested 230 individuals with normosmia, hyposmia, and anosmia using grocery-available powders. Initially, 30 different substances were investigated. Subjects identified each substance using a list with 4 verbal items (forced choice). After preliminary experiments, 20 items were selected according to the degree to which they were identified by normosmic and anosmic subjects. Orthonasal olfactory function was assessed psychophysically using "sniffin' sticks," which includes tests for odor identification, discrimination, and butanol odor thresholds. In addition, anosmia was confirmed electrophysiologically by means of olfactory-evoked potentials. In healthy subjects, there was a test-retest reliability correlation of r(27) = 0.76 for retronasal olfactory function, which is similar to other odor identification tests. Retronasal testing in normosmic subjects allowed for the discrimination of sex-related differences, with women scoring higher than men (P =.007), and the identification of a slight decrease with age (r(120) = -0.20; P =....Continue Reading

Citations

Apr 8, 2014·Medical Science Monitor : International Medical Journal of Experimental and Clinical Research·Murat SalihogluHakan Tekeli
May 6, 2014·International Journal of Pediatric Otorhinolaryngology·Aytug AltundagHakan Tekeli
Sep 4, 2013·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Ilona CroyThomas Hummel
Mar 13, 2014·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Melih CayonuGürkan Kayabasoglu
Dec 4, 2014·HNO·V A SchrieverA Welge-Lüssen
Apr 8, 2014·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Maria HeckelChristoph Ostgathe
Jan 1, 2010·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Onder GöktasBasile Nicolas Landis
Mar 20, 2010·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Ph RombauxT Hummel
Jul 1, 2011·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·C HuartPh Rombaux
Nov 8, 2011·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Sarah Bettina DahlslettFranca Fleiner
Aug 7, 2007·HNO·T HummelB N Landis
Oct 13, 2009·Journal of Neurology·Basile Nicolas LandisThomas Hummel
Apr 29, 2004·Behavioral Neuroscience·Stefan Heilmann, Thomas Hummel
Mar 20, 2012·Physiology & Behavior·Viola Bojanowski, Thomas Hummel
Jul 2, 2011·Biological Psychology·Pierre MauragePhilippe de Timary
May 12, 2009·Neuroscience Letters·Antje Welge-LüssenThomas Hummel
Sep 16, 2009·The Laryngoscope·Basile N LandisPierre R Burkhard
Jul 12, 2008·Chemistry & Biodiversity·Thomas Hummel
Feb 25, 2009·The Laryngoscope·Bertold RennerGerd Kobal
Dec 19, 2013·The Laryngoscope·Murat SalihoğluFatih Özdağ
Nov 6, 2013·Movement Disorders : Official Journal of the Movement Disorder Society·Antje HaehnerHeinz Reichmann
Sep 17, 2014·The Laryngoscope·Gregory ReychlerPhilippe Rombaux
Nov 27, 2004·Otolaryngologic Clinics of North America·Bradley J Goldstein, Andrew P Lane
May 24, 2005·International Journal of Pediatric Otorhinolaryngology·Iordanis KonstantinidisGeorge Kontzoglou
Feb 20, 2015·Multisensory Research·Léa GagnonMaurice Ptito
Sep 20, 2015·European Annals of Otorhinolaryngology, Head and Neck Diseases·D T NguyenR Jankowski
Apr 1, 2014·European Annals of Otorhinolaryngology, Head and Neck Diseases·S FonteynP Rombaux
Nov 26, 2014·Chemical Senses·Aytug AltundagThomas Hummel
May 2, 2016·Current Allergy and Asthma Reports·Philippe RombauxT Hummel
Sep 15, 2016·Frontiers in Systems Neuroscience·Rodrigo AranedaAnne G De Volder
Mar 31, 2016·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Omer SaglamBilal Cetin
Sep 7, 2012·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Philippe RombauxThomas Hummel
Jan 20, 2011·American Journal of Rhinology & Allergy·Franca FleinerOender Goektas
Aug 9, 2011·American Journal of Rhinology & Allergy·Boris R HaxelAxel Muttray
Aug 15, 2018·American Journal of Rhinology & Allergy·Kimia G GanjaeiRodney J Schlosser
Jan 31, 2009·American Journal of Rhinology·Philippe RombauxThomas Hummel
Nov 15, 2007·American Journal of Rhinology·Philippe RombauxThomas Hummel
Sep 12, 2018·International Forum of Allergy & Rhinology·Marco Aurélio FornazieriRichard L Doty

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