PMID: 11906545Mar 22, 2002Paper

Clinical behavior of 203 stage II endometrial cancer cases: the impact of primary surgical approach and of adjuvant radiation therapy

International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society
E SartoriV Zanagnolo

Abstract

The aim of this study was to verify the impact of primary surgical approach and adjuvant radiation therapy (RT) on survival, recurrence rate, and pattern of relapse in stage II endometrial cancer patients. Two hundred three subjects were retrospectively reviewed; 135 (66%) underwent simple hysterectomy (SH) and 68 (34%) radical hysterectomy (RH). Sixty-six of 111 (59%) of stage IIA and 67 of 92 (73%) of stage IIB patients underwent adjuvant radiation therapy. Actuarial survival rates for stage IIA and IIB were 86% and 74% at 5 years and 82% and 68% at 10 years, respectively. Survival rates by surgical procedure were 79% in the SH group and 94% in the RH group at 5 years and 74% and 94% at 10 years, respectively (P < 0.05). The overall recurrence rate was 13.8% (28/203); by adjuvant treatment it was 18.6% (13/70) in the observation group and 11.3% (15/133) in the RT group. Most of the relapses were locoregional in the observation group and distant in the RT group. Survival rates by RT were not statistically different. Subjects treated with RH improved their survival compared with the SH group; the difference was significant, but randomized studies should confirm this trend. Although adjuvant RT seemed to reduce the recurrence ra...Continue Reading

References

Sep 1, 1991·International Journal of Radiation Oncology, Biology, Physics·S A ReisingerM Mohiuddin
May 1, 1989·Gynecologic Oncology·R A BoothbyJ J Mikuta
Jun 1, 1987·Gynecologic Oncology·S K ChambersP E Schwartz
Apr 15, 1985·American Journal of Obstetrics and Gynecology·P J DiSaiaJ A Blessing
Aug 1, 1982·Gynecologic Oncology·M L BermanH G Ball
Mar 1, 1995·Annals of Surgical Oncology·M P BoenteG D Wilbanks
Mar 1, 1993·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·D ChassagneG Michel
Nov 1, 1995·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·M SerraN Baldini
Aug 1, 1996·Obstetrics and Gynecology·N TakeshimaK Hasumi
May 20, 1998·International Journal of Radiation Oncology, Biology, Physics·K B HartA T Porter
Mar 4, 1999·Gynecologic Oncology·T KamuraH Nakano
Jul 1, 1999·Gynecologic Oncology·G H Eltabbakh, A D Moore
Sep 1, 1999·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·M HiraiO Matsuzaki
Mar 31, 2000·Gynecologic Oncology·J WylieA Fyles

❮ Previous
Next ❯

Citations

Dec 23, 2011·Strahlentherapie und Onkologie : Organ der Deutschen Röntgengesellschaft ... [et al]·S Marnitz, C Köhler
Jul 9, 2010·Obstetrics and Gynecology International·Ying Zhang, Jian Wang
Dec 18, 2007·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·J J JobsenS Siesling
Oct 16, 2004·Current Oncology Reports·Gunnar Kristensen, Claes Tropé
Mar 24, 2010·Archives of Gynecology and Obstetrics·Florian MuellerU Ulrich
Jan 17, 2012·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·H S KimJ W Kim
Apr 4, 2013·Taiwanese Journal of Obstetrics & Gynecology·Yukiharu Todo, Noriaki Sakuragi
Mar 1, 2011·Surgical Pathology Clinics·Mario M Leitao, Richard R Barakat
Oct 4, 2015·Gynecologic Oncology·Devarati MitraAkila N Viswanathan
Apr 29, 2008·Clinical Oncology : a Journal of the Royal College of Radiologists·C M Holland
Jan 1, 2008·International Journal of Radiation Oncology, Biology, Physics·Scott C Cozad
Apr 4, 2006·Journal of Evaluation in Clinical Practice·Marieke A L van LankveldMarion A van Eijkeren
Jan 3, 2013·The Journal of Obstetrics and Gynaecology Research·Yukiharu Todo, Noriaki Sakuragi
Feb 22, 2005·Gynecologic Oncology·Justine M BriëtHans W Nijman
Oct 5, 2015·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·Frédéric AmantCarien L Creutzberg
Jan 13, 2009·American Journal of Obstetrics and Gynecology·Jason D WrightThomas J Herzog
Apr 30, 2016·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Timothy P HannaMichael B Barton
Oct 4, 2012·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·Frédéric AmantCarien L Creutzberg
Apr 25, 2014·Journal of Gynecologic Oncology·Jonathan E FrandsenDavid K Gaffney
Oct 1, 2014·European Heart Journal. Acute Cardiovascular Care·Fabrizio RicciSabina Gallina
Sep 21, 2017·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Nejat OzgulTayup Simsek
Jun 13, 2017·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Jinhong JungYong Bae Kim
Oct 12, 2018·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·Frédéric AmantCarien L Creutzberg
Oct 23, 2010·Obstetrics and Gynecology·Yoh WatanabeHiroshi Hoshiai
May 2, 2007·Obstetrics and Gynecology·David E CohnJeffrey M Fowler
Mar 1, 2012·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Martin KoskasRoman Rouzier
Jan 31, 2016·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Michelle M BoisenJohn T Comerci
May 28, 2009·Journal of Gynecologic Oncology·Jin Hwi KimJong Sup Park
Feb 3, 2006·Gynäkologisch-geburtshilfliche Rundschau·Dorothee GrundSimone Marnitz
Apr 11, 2018·Scientific Reports·Ryan K OroscoQuyen T Nguyen
May 23, 2020·World Journal of Surgical Oncology·Salim Abraham Barquet-MuñozR A Salcedo-Hernández
Jan 8, 2021·Journal of Obstetrics and Gynaecology Canada : JOGC = Journal D'obstétrique Et Gynécologie Du Canada : JOGC·Genevieve K LennoxLilian T Gien
Aug 20, 2021·The Journal of Obstetrics and Gynaecology Research·Ming WangYumei Wu
Nov 5, 2021·Current Oncology Reports·Michael D Toboni, Matthew A Powell

❮ Previous
Next ❯

Related Concepts

Related Feeds

Adenocarcinoma, Clear Cell

Clear Cell Adenocarcinoma is a tumor that arises in the female genital tract and is characterized by cells that appear clear under the microscope. Discover the latest research here.