Clinical case series of pediatric hepatic angiosarcoma

Pediatric Blood & Cancer
Kalee L GrassiaDenise M Adams

Abstract

Hepatic angiosarcoma is a rare, aggressive, malignant neoplasm with fewer than 50 cases reported in children. Prognosis is poor, with a minority surviving beyond 2 years after diagnosis. We report eight cases of pediatric hepatic angiosarcoma, diagnosed at a mean age of 3 years. Seven were initially diagnosed with an infantile hepatic hemangioendothelioma (IHHE) or hemangioma and the eighth with a "vascular tumor." Two patients, who received liver transplant, survived. We suggest hepatic hemangiomas can rarely transform into angiosarcomas and a subset of IHHEs (Type II) are actually a low-grade form of angiosarcoma rather than a benign lesion.

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Citations

Apr 24, 2019·Pediatric Transplantation·Kristy PilbeamSrinath Chinnakotla
Feb 23, 2020·Japanese Journal of Clinical Oncology·Dong ZengBo Zhu
Oct 18, 2019·Pediatric Radiology·Govind B ChavhanAbha A Gupta
Nov 9, 2020·The Journal of Emergency Medicine·Matthew Vanston SpeicherRichard C Childers
Oct 23, 2020·Pediatrics International : Official Journal of the Japan Pediatric Society·Masaya YamotoNaoto Urushihara
Feb 16, 2021·Clinics in Perinatology·Michael Briones, Denise Adams
Mar 7, 2021·Diagnostics·Bryony LucasIrina Pateva
Mar 13, 2021·Surgical Oncology Clinics of North America·Rebecka MeyersGreg M Tiao
Oct 19, 2020·Seminars in Pediatric Surgery·Anna McGuireBelinda Hsi Dickie
Oct 19, 2020·Seminars in Pediatric Surgery·Sara A MansfieldIonela Iacobas
Apr 24, 2021·World Journal of Gastrointestinal Oncology·Sami Bannoura, Juan Putra

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