Clinical characteristics and influencing factors of patients with novel coronavirus pneumonia combined with liver injury in Shaanxi region

Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology
N YaoW Kang

Abstract

Objective: To understand the clinical characteristics, change of liver function, influencing factors and prognosis in hospitalized patients with coronavirus disease-19 (COVID-19) combined with liver injury. Methods: The general conditions, biochemical indicators of liver, blood clotting mechanism, routine blood test, UGT1A1 * 28 gene polymorphism and other data of 40 cases with COVID-19 admitted to the isolation ward of Tangdu Hospital were retrospectively analyzed. The clinical characteristics, influencing factors and prognosis of liver injury in patients with liver injury group and those with normal liver function group were compared. The mean of two samples in univariate analysis was compared by t-test and analysis of variance. The counting data was measured by χ(2) tests. The non-normal distribution measurement data were described by the median, and the non-parametric test was used. Statistically significant influencing factors were used as the independent variables in univariate analysis. Multiple logistic regression analysis was used to analyze the main influencing factors of liver injury. Results: Of the 40 cases, 25 were male (62.5%) and 15 were female (37.5%), aged 22 to 83 (53.87 ± 15.84) years. Liver injury was occur...Continue Reading

Citations

Jul 6, 2020·Hepatology International·Praveen Kumar-MVishal Sharma
Jan 15, 2021·World Journal of Hepatology·Prajna AnirvanSanjaya K Satapathy
Feb 9, 2021·World Journal of Clinical Cases·Mei-Wen HanDong Xi
May 21, 2021·Scientific Reports·Khalid BzeiziDieter Broering
Jul 10, 2021·World Journal of Gastroenterology : WJG·Ting-Ting CaoHua-Qin Pan
Aug 10, 2021·World Journal of Gastroenterology : WJG·Dina Zakaria MohamedMohamed Abdelhalem Farag
Aug 28, 2021·World Journal of Clinical Cases·Mostafa AlfishawyKarim M Soliman

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