Clinical characteristics and long-term prognosis of contemporary patients with vasospastic angina: Ethnic differences detected in an international comparative study

International Journal of Cardiology
Koichi SatoJapanese Coronary Spasm Association

Abstract

Possible ethnic differences in clinical characteristics and long-term prognosis of contemporary patients with vasospastic angina (VSA) remain to be elucidated. The Japanese Coronary Spasm Association (JCSA) conducted an international, prospective, and multicenter registry study for VSA patients. A total of 1457 VSA patients (Japanese/Caucasians, 1339/118) were enrolled based on the same diagnostic criteria. Compared with Caucasian patients, Japanese patients were characterized by higher proportions of males (68 vs. 51%) and smoking history (60 vs. 49%). Japanese patients more often had angina especially during the night and early morning hours, compared with Caucasians. Ninety-five percent of Japanese and 84% of Caucasian patients underwent pharmacological provocation test. Importantly, no significant differences in the patterns of coronary spasm were apparent, with diffuse spasm most frequently noted in both ethnicities. The prescription rate of calcium-channel blockers was higher in Japanese (96 vs. 86%), whereas the uses of nitrates (46 vs. 59%), statins (43 vs. 65%), renin-angiotensin-system inhibitors (27 vs. 51%), and β-blockers (10 vs. 24%) were more common in Caucasian patients. Survival rate free from major adverse car...Continue Reading

Citations

Jan 30, 2020·Current Cardiology Reports·Matthieu Pelletier-Galarneau, Vasken Dilsizian
Oct 28, 2020·Cardiovascular Intervention and Therapeutics·Satoru SuzukiKenichi Tsujita
Mar 20, 2021·JACC. Cardiovascular Interventions·Kensuke NishimiyaHiroaki Shimokawa
Aug 3, 2020·JACC. Cardiovascular Interventions·Emmanuel Sorbets, Alexandre Cinaud
Nov 28, 2021·BMJ : British Medical Journal·John F BeltrameChris Zeitz

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