Clinical characteristics and outcomes of COVID-19 patients with gastrointestinal symptoms admitted to Jianghan Fangcang Shelter Hospital in Wuhan, China

Journal of Medical Virology
Ting ZhengHui Sun

Abstract

Coronavirus disease 2019 (COVID-19) is a health emergency worldwide, and gastrointestinal (GI) symptoms are increasingly reported in COVID-19 patients. However, sample size was small and the incidence of GI symptoms in patients was variable across studies, and the correlation between these symptoms and clinical outcomes remains incompletely understood. The objective of this study is to compare clinical characteristics and outcomes between patients with and without GI symptoms admitted to Jianghan Fangcang Shelter Hospital in Wuhan. This retrospective study recruited 1320 COVID-19 patients admitted to hospital from 5 February 2020 to 9 March 2020. On the basis of the presence of GI symptoms, the sample was divided into a GI group (n = 192) and a non-GI group (n = 1128). The three most common GI symptoms were diarrhea (8.1%), anorexia (4.7%), and nausea and vomiting (4.3%). The rate of clinical deterioration was significantly higher in the GI group than in the non-GI group (15.6% vs. 10.1%, P = .032). GI symptoms (P = .045), male gender P < .001), and increased C-reactive protein (P = .008) were independent risk factors for clinical worsening. This study demonstrated that the rate of clinical deterioration was significantly highe...Continue Reading

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Citations

Nov 12, 2020·Microorganisms·Lakshya Sharma, Antonio Riva
Nov 16, 2020·Scandinavian Journal of Immunology·Fatemeh MaghoolSamane Mohammadzadeh
Jan 9, 2021·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·Bradley J LangfordDerek R MacFadden
Feb 2, 2021·Genes & Diseases·Jilei ZhangJun Sun
Jul 31, 2021·Essays in Biochemistry·Damien A LeachCharlotte L Bevan
Aug 2, 2021·Digestive Diseases and Sciences·Giulia ConcasMaria Antonietta Marcialis
Nov 6, 2021·Journal of Digestive Diseases·Meng Meng ZhangJia Ming Qian

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