Clinical characteristics and outcomes of patients with right congenital diaphragmatic hernia: A population-based study

Journal of Pediatric Surgery
Catherine K BeaumierCanadian Pediatric Surgery Network

Abstract

The purpose of this study was to compare RCDH to LCDH from the perspective of prenatal diagnosis, illness severity, treatment, and outcome. A retrospective study of all cases of CDH registered in the Canadian Pediatric Surgery Network (CAPSNet) database from 2005 to 2013 was conducted. Side of defect comparisons were made by prenatal diagnostic features, birth demographic data, intensity of medical treatment, timing and type of surgery, and outcomes. Outcomes prediction with logistic regression modeling using side of defect as an exploratory covariate was performed. The study cohort included 498 patients, of which 84 (17%) cases had RCDH. Prenatal diagnosis was more commonly made for LCDH. No difference existed in perinatal risk factors (GA, illness severity (SNAP-II) score, associated anomalies), preoperative treatment intensity (use of vasodilators, inotropes), timing of surgery, ventilation days, need for ECMO, LOS, and overall survival. Significant differences between RCDH and LCDH were detected for patch repair rate (48.2% vs. 30.6%; p=0.036) and recurrence (4.1% vs. 0.6%; p=0.038). Stepwise regression modeling identified side of hernia as independently predictive of need for patch. Overall, little difference exists betwee...Continue Reading

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Citations

Jun 28, 2016·Journal of Pediatric Surgery·Emily A PartridgeHolly L Hedrick
Aug 28, 2016·The American Journal of Pathology·Patricia K DonahoeFrances A High
Jan 7, 2018·Archives of Disease in Childhood. Fetal and Neonatal Edition·Anna-May LongUNKNOWN BAPS-CASS
May 16, 2019·Pediatric Surgery International·Kamal AliAnne Greenough
Oct 7, 2021·Wiener medizinische Wochenschrift·Anna HoferFranz Hornath

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