Clinical characteristics and prognostic factors in COVID-19 patients aged ≥80 years

Geriatrics & Gerontology International
Marcello CovinoFrancesco Franceschi

Abstract

The aim of the present study was to describe the clinical presentation of patients aged ≥80 years with coronavirus disease 2019 (COVID-19), and provide insights regarding the prognostic factors and the risk stratification in this population. This was a single-center, retrospective, observational study, carried out in a referral center for COVID-19 in central Italy. We reviewed the clinical records of patients consecutively admitted for confirmed COVID-19 over a 1-month period (1-31 March 2020). We excluded asymptomatic discharged patients. We identified risk factors for death, by a uni- and multivariate Cox regression analysis. To improve model fitting and hazard estimation, continuous parameters where dichotomized by using Youden's index. Overall, 69 patients, aged 80-98 years, met the inclusion criteria and were included in the study cohort. The median age was 84 years (82-89 years is interquartile range); 37 patients (53.6%) were men. Globally, 14 patients (20.3%) presented a mild, 30 (43.5%) a severe and 25 (36.2%) a critical COVID-19 disease. A total of 23 (33.3%) patients had died at 30 days' follow up. Multivariate Cox regression analysis showed that severe dementia, pO2 ≤90 at admission and lactate dehydrogenase >464 U/...Continue Reading

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Citations

Oct 2, 2020·Geriatrics & Gerontology International·Veerendra Kumar Arumalla, Aruna Bholenath Patil
Oct 2, 2020·Geriatrics & Gerontology International·Li Feng TanAlexander Wenjun Yip
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May 11, 2021·Geriatrics & Gerontology International·Kana KazawaShinya Ishii
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Methods Mentioned

BETA
X‐ray

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Medcalc

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