Clinical Characteristics and Surgical Management of Gastrointestinal Schwannomas.

BioMed Research International
Xin WuXiaodong He

Abstract

Schwannomas are tumors arising from Schwan cells of the neural sheath. Gastrointestinal schwannomas (GS) are rare and easily confused with a heterogeneous group of neuroectodermal or mesenchymal neoplasms. The aim of the present study is to analyze the clinicopathological features, surgical management methods, and long-term prognoses of GS patients. Between August 2004 and July 2019, 51 patients with GS were treated at the Peking Union Medical College Hospital. The medical records were reviewed retrospectively. A database containing demographic characteristics, clinical symptoms, imaging tests, operation details, pathological results, and prognoses was constructed and analyzed. GS accounted for 2.0% of all schwannomas. The cohort comprised 19 men (37.3%) and 32 women (62.7%). The mean age was 55.7 ± 11.4 years. The most common symptom was abdominal pain (29.4%). Twenty-seven patients (52.9%) were asymptomatic and diagnosed incidentally. The most common tumor location of GS was the stomach (90.2%). S-100 had the highest positive rate (100%) in immunohistochemical staining. Forty-six patients (90.2%) were followed-up at a mean period of 49.5 ± 41.4 months. Forty-four patients (95.7%) survived without tumor, 1 patient survived wit...Continue Reading

References

Mar 5, 1998·The British Journal of Radiology·N R BeesE M Kiely
May 15, 1998·European Journal of Gastroenterology & Hepatology·R J LoffeldA B van der Putten
Sep 27, 2000·Histology and Histopathology·T Nishida, S Hirota
Feb 25, 2005·AJR. American Journal of Roentgenology·Angela D LevyLeslie H Sobin
Mar 17, 2010·Gastrointestinal Endoscopy·Mohamed A MekkyVikram Bhatia
May 12, 2011·Journal of Gastroenterology and Hepatology·Sung Han ParkTae Yong Jeon
Dec 6, 2011·Human Pathology·Lysandra VoltaggioMarkku Miettinen
Jan 27, 2012·Journal of Medical Case Reports·Masashi TakemuraAkishige Kanazawa
Aug 28, 2012·Case Reports in Surgery·William YoonRichard Berri
Jan 18, 2013·World Journal of Gastroenterology : WJG·Dan-Dan ZhongJian-Ting Cai
Oct 11, 2013·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Hyunseon C KangKhaled M Elsayes
Apr 2, 2014·Gastroenterology Research and Practice·Lijun ZhengJiafu Ji
Sep 26, 2015·Indian Journal of Surgical Oncology·M R Sreevathsa, Gotam Pipara
Jan 16, 2016·Journal of Medical Case Reports·Aminder SinghNeena Sood
Mar 16, 2016·Clinical Endoscopy·Jong Min YoonGeun Am Song
Oct 21, 2016·Arquivos Brasileiros De Cirurgia Digestiva : ABCD = Brazilian Archives of Digestive Surgery·Rafael Dienstmann Dutra VilaAdriano Calcagnotto Garcia
Dec 1, 2010·Gastroenterology Research·Menno H RaberJoost M Klaase
Jun 3, 2017·Case Reports in Gastrointestinal Medicine·Bao-Guang HuHe-Sheng Li
Mar 23, 2018·Oxford Medical Case Reports·Tagore SunkaraVinaya Gaduputi
Jul 5, 2018·World Journal of Surgical Oncology·Ali BohlokGabriel Liberale
Dec 21, 2018·International Journal of Surgery Case Reports·Daniel ParamythiotisAntonis Michalopoulos
Mar 12, 2019·Canadian Association of Radiologists Journal = Journal L'Association Canadienne Des Radiologistes·Jian WangHong-Jie Hu
May 3, 2019·Gastroenterology Research and Practice·Zhenbo ShuZhongmin Li
Sep 29, 2019·World Journal of Gastrointestinal Oncology·Jesús Morales-MazaHeriberto Medina-Franco

❮ Previous
Next ❯

Methods Mentioned

BETA
surgical resection
biopsies
biopsy

Software Mentioned

Statistical Package for Social Sciences software ( SPSS

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.