Abstract
Stent thrombosis (ST) is rare, but is associated with significant morbidity and mortality. We analyzed data from the British Columbia (BC) Registry from April 2011-January 2012. 101 ST cases were reported and verified. Based on timing, ST was considered early (≤30days) in 35.6%, late (>30days-1year) in 17.8% and very late (>1year) in 46.5%. The majority (68.5%) presented with STEMI, and the remaining with non-STEMI (31.5%). Most vessels were functionally occluded (TIM1 flow grade ≤1 in 67.1%). Thrombus burden was high (TIMI thrombus grade ≥4 in 77.2%). Aspiration thrombectomy was performed in 41% of cases. New stents were implanted in 62.4% cases. Intra-coronary imaging was low (11%). At the original stent implantation, STEMI was the clinical presentation in 39.6%, the lesion was complex in 62.1%, and thrombus was visualized in 23.0%. Prognosis after ST was unfavorable with high mortality (11.9% at 30days and 16.8% at one year), and further revascularization (5.0% repeat PCI and 6.9% coronary artery bypass graft surgery). Early ST was associated with worse clinical outcome compared to late/very late ST: 30-day mortality at 22.2% versus 6.2% (p=0.02), and 1-year mortality at 27.8% versus 10.8% (p=0.05). In this prospective regis...Continue Reading
References
Aug 15, 1991·The American Journal of Cardiology·M S HuberM R Mooney
Aug 1, 1988·Circulation·T J RyanW L Winters
May 5, 2005·JAMA : the Journal of the American Medical Association·Ioannis IakovouAntonio Colombo
Feb 27, 2007·Lancet·Joost DaemenPatrick W Serruys
May 2, 2007·Circulation·Donald E CutlipUNKNOWN Academic Research Consortium
May 9, 2007·Circulation·Stéphane CookStephan Windecker
Mar 29, 2008·American Heart Journal·Michael J RinaldiDavid J Cohen
Jun 6, 2009·Journal of Interventional Cardiology·Gilles LemesleRon Waksman
Jun 17, 2009·Circulation·Ajay J KirtaneGregg W Stone
May 1, 2010·Journal of the American College of Cardiology·Douglass A Morrison
Jun 23, 2010·Circulation·Takeshi KimuraUNKNOWN RESTART Investigators
Sep 13, 2011·The American Journal of Cardiology·Karim D MahmoudBart J G L de Smet
Nov 9, 2011·Circulation·Glenn N LevineHenry H Ting
Jan 11, 2012·European Heart Journal·Giovanna SarnoStefan James
Mar 1, 2012·JACC. Cardiovascular Interventions·Ehrin J ArmstrongKendrick A Shunk
Nov 23, 2012·EuroIntervention : Journal of EuroPCR in Collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology·Yaojun ZhangShao-Liang Chen
Mar 4, 2014·Journal of the American College of Cardiology·David CarrickColin Berry
Apr 2, 2014·The American Journal of Cardiology·Jung-Min AhnSeung-Jung Park
Oct 25, 2014·JACC. Cardiovascular Interventions·Bimmer E ClaessenGeorge D Dangas
Apr 9, 2015·The New England Journal of Medicine·Sanjit S JollyUNKNOWN TOTAL Investigators
Apr 26, 2015·The American Journal of Cardiology·Eric A SecemskyUNKNOWN PROTECT Trial Investigators
Citations
Feb 23, 2020·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Samer NoamanUNKNOWN Melbourne Interventional Group Investigators
Jul 25, 2017·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Kuljit SinghMichel Le May
Jul 22, 2020·Journal of Thrombosis and Thrombolysis·Yi-Xing YangJing Gao