Clinical characteristics, comorbidities and outcomes among persons with HIV hospitalized with coronavirus disease 2019 in Atlanta, Georgia.

AIDS
Lauren F CollinsAnandi N Sheth

Abstract

There are limited data describing the presenting characteristics and outcomes among US persons with HIV (PWH) requiring hospitalization for coronavirus disease 2019 (COVID-19). We performed a case series of all PWH sequentially admitted with COVID-19 from 8 March 2020 to 23 April 2020 at three hospitals in Atlanta, Georgia. Sociodemographic, clinical and HIV-associated characteristics were collected. Of 530 confirmed COVID-19 cases hospitalized during this period, 20 occurred among PWH (3.8%). The median age was 57 (Q1-Q3, 48-62) years, 65% were men, and 85% were non-Hispanic Black. Presenting median symptom duration was 5 (Q1-Q3, 3-7) days; cough (90%), fever (65%), malaise (60%) and dyspnea (60%) were most common. On admission, 40% of patients required oxygenation support and 65% had an abnormal chest radiograph. Median length of hospitalization was 5 (Q1-Q3, 4-12) days, 30% required intensive care, 15% required intubation, and 15% died. Median CD4 cell count prior to admission was 425 (Q1-Q3, 262-815) cells/μl and 90% of patients had HIV-1 RNA less than 200 copies/ml. Half of the patients had at least five comorbidities; hypertension (70%), dyslipidemia (60%) and diabetes (45%) were most prevalent. All three patients who die...Continue Reading

References

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Citations

Aug 11, 2020·AIDS·Michael Saag
Nov 9, 2020·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Lauren F Collins
Sep 10, 2020·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Dima DandachiJeremy Chow
Dec 17, 2020·International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases·Justyna D KowalskaRaimonda Matulionyte
Jan 5, 2021·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Virginia A Triant, Rajesh T Gandhi
Oct 17, 2020·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Leonardo CalzaPierluigi Viale
Nov 14, 2020·Current Opinion in HIV and AIDS·Lillian B BrownMonica Gandhi
Apr 4, 2021·International Journal of Environmental Research and Public Health·Kai Wei LeeMunn Sann Lye
May 3, 2021·Journal of the Formosan Medical Association = Taiwan Yi Zhi·Wang-Da LiuShan-Chwen Chang
Jun 30, 2021·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·Juan BerenguerInmaculada Jarrín
May 16, 2021·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Vanessa SardáMonica Merçon
Aug 17, 2021·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Jennifer J ChangRulin C Hechter

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Methods Mentioned

BETA
reverse transcription-PCR

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