Clinical characteristics in patients with SARS-CoV-2/HBV co-infection

Journal of Viral Hepatitis
Liping ChenJilin Cheng

Abstract

COVID-19 has become a global pandemic and garnered international attention. Although the clinical features of COVID-19 related liver injury have been investigated, there have been no reports and studies on the clinical characteristics of COVID-19 patients co-infected with Hepatitis B Virus (HBV). This study aimed to evaluate whether SARS-CoV-2/HBV co-infection could influence liver function and the disease outcome. All 326 confirmed COVID-19 cases in Shanghai Public Health Clinical Center (The COVID-19 designated hospital in Shanghai, China) from January 20, 2020 to February 24, 2020 were enrolled and followed up until February 29 in this study. The clinical, laboratory data and the length of stay were collected and analyzed retrospectively. 20 patients with HBV co-infection (6.1%) and 306 patients (93.9%) without HBV infection showed no differences in the level of liver function parameters. However, compared with HBsAg- patients [145.4 mg/L (103.9-179.2)], HBsAg+ patients had a lower level of prealbumin [(102.3 mg/L (76.22-160.2), P=.0367]. There were also no significant differences for the discharge rate and the length of stay between two groups. Taken together, we found no evidence that SARS-CoV-2/HBV co-infection could aggr...Continue Reading

References

Oct 31, 2014·World Journal of Gastroenterology : WJG·Hsin-Yun SunChien-Ching Hung
Feb 8, 2020·JAMA : the Journal of the American Medical Association·Dawei WangZhiyong Peng
Mar 8, 2020·The Lancet. Gastroenterology & Hepatology·Chao ZhangFu-Sheng Wang
Mar 15, 2020·Liver International : Official Journal of the International Association for the Study of the Liver·Ling XuXin Zheng
Apr 14, 2020·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Zhenyu FanJilin Cheng
Apr 17, 2020·Journal of Hepatology·Qingxian CaiLin Xu
May 3, 2020·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Fang LeiYufeng Yuan
Jun 27, 2020·Obstetrics and Gynecology·Ilia Bresesti, Lorella Rossi

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Citations

Dec 18, 2020·Journal of Medical Virology·Soumya SarkarAkhil Kant Singh
Feb 9, 2021·World Journal of Clinical Cases·Mei-Wen HanDong Xi
Mar 18, 2021·World Journal of Gastroenterology : WJG·Tian-Dan Xiang, Xin Zheng
May 26, 2021·Journal of Medical Virology·Parisa S AghbashHossein B Baghi
Dec 18, 2020·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Antonio SavianoThomas F Baumert
May 8, 2021·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Terry Cheuk-Fung YipGrace Lai-Hung Wong
Jun 26, 2021·World Journal of Gastroenterology : WJG·Yue CaiShao-Wei Li
Jul 6, 2021·Hepatology Communications·Miguel Angel Martinez, Sandra Franco

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