Clinical characteristics of 312 hospitalized older patients with COVID-19 in Wuhan, China

Archives of Gerontology and Geriatrics
Tao LiJun Duan

Abstract

Much of the previous research on COVID-19 was based on all population. But substantial numbers of severe episodes occur in older patients. There is a lack of data about COVID-19 in older adults. The aims of this study were to analyze the clinical characteristics of older adult patients with COVID-19. Retrospective study of older patients hospitalized with COVID-19 from February 1 st to March 31 st, 2020 was conducted in the Sino-French New City Branch of Tongjing Hospital in Wuhan, China. According to the degree of severity of COVID-19 during hospitalization, 312 older patients were divided into non-severe and severe cases. the mean age of the patients was 69.2 ± 7.3 years, and 47.4 % of patients had exposure history. 77.2 % of patients had a co-morbidity, with hypertension being the most common (57.1 %), followed by diabetes (38.8 %) and cardiovascular disease (29.8 %). Multivariable regression showed increasing odds of severe COVID-19 associated with age(OR 1.59, 95 %CI 1.13-2.08), SOFA score(OR 5.89, 95 %CI 3.48-7.96), APACHEⅡ score(OR 3.13, 95 %CI 1.85-5.62), platelet count<125 × 109/L(OR 2.36, 95 %CI 1.03-4.14), d-dimer (OR 4.37, 95 %CI 2.58-7.16), creatinine>133 μmol/L(OR 1.85, 95 %CI 1.12-3.04), interleukin-6(OR 4.32, 95...Continue Reading

Citations

Sep 16, 2020·Obesity Reviews : an Official Journal of the International Association for the Study of Obesity·Tu-Hsuan ChangLuan-Yin Chang
Aug 26, 2020·QJM : Monthly Journal of the Association of Physicians·Dong YangAnlin Peng
Sep 13, 2020·Journal of Community Health·Farha Musharrat Noor, Md Momin Islam
Feb 10, 2021·Critical Care : the Official Journal of the Critical Care Forum·Maria Clara Saad MenezesJosé Otavio Costa Auler
Jul 20, 2021·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Allison MarzilianoLiron Sinvani
Jul 27, 2021·Computational and Structural Biotechnology Journal·Daniele MercatelliPietro Hiram Guzzi
Apr 6, 2021·Aging and Disease·Xin DingUNKNOWN Chinese Critical Ultrasound Study Group

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Methods Mentioned

BETA
bronchoalveolar lavage

Software Mentioned

SPSS

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