Clinical Characteristics of Coronavirus Disease 2019 in China.

The New England Journal of Medicine
Wei-Jie GuanChina Medical Treatment Expert Group for Covid-19

Abstract

Since December 2019, when coronavirus disease 2019 (Covid-19) emerged in Wuhan city and rapidly spread throughout China, data have been needed on the clinical characteristics of the affected patients. We extracted data regarding 1099 patients with laboratory-confirmed Covid-19 from 552 hospitals in 30 provinces, autonomous regions, and municipalities in mainland China through January 29, 2020. The primary composite end point was admission to an intensive care unit (ICU), the use of mechanical ventilation, or death. The median age of the patients was 47 years; 41.9% of the patients were female. The primary composite end point occurred in 67 patients (6.1%), including 5.0% who were admitted to the ICU, 2.3% who underwent invasive mechanical ventilation, and 1.4% who died. Only 1.9% of the patients had a history of direct contact with wildlife. Among nonresidents of Wuhan, 72.3% had contact with residents of Wuhan, including 31.3% who had visited the city. The most common symptoms were fever (43.8% on admission and 88.7% during hospitalization) and cough (67.8%). Diarrhea was uncommon (3.8%). The median incubation period was 4 days (interquartile range, 2 to 7). On admission, ground-glass opacity was the most common radiologic fin...Continue Reading

Associated Clinical Trials

Apr 24, 2020·Maria Julia Cremona
Apr 24, 2020·Usha Perepu
Aug 4, 2020·Jaime Daniel Mondragón Uribe
Aug 5, 2020·Jaime Daniel Mondragón Uribe

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Citations

Feb 29, 2020·The New England Journal of Medicine·Anthony S FauciRobert R Redfield
Mar 4, 2020·Intensive Care Medicine·Yaseen M ArabiSteve Webb
Mar 12, 2020·Annals of Internal Medicine·Michael Klompas
Mar 4, 2020·Journal of Medical Virology·JingCheng ZhangYaDong Xue
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Mar 19, 2020·The New England Journal of Medicine·Xiaoxia LuUNKNOWN Chinese Pediatric Novel Coronavirus Study Team
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Mar 31, 2020·Alimentary Pharmacology & Therapeutics·Yuan TianYan He
Apr 3, 2020·Journal of Clinical Medicine·Israel Júnior Borges do NascimentoMilena Soriano Marcolino
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Software Mentioned

R
R Foundation for Statistical Computing
ArcGIS

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