Clinical characteristics of dry eye with ocular neuropathic pain features: comparison according to the types of sensitization based on the Ocular Pain Assessment Survey.

BMC Ophthalmology
Jonghwa KimKyung Chul Yoon

Abstract

To compare the clinical characteristics of dry eye patients with ocular neuropathic pain features according to the types of sensitization based on the Ocular Pain Assessment Survey (OPAS). Cross-sectional study of 33 patients with dry eye and ocular neuropathic pain features. All patients had a comprehensive ophthalmic assessment including detailed history, the intensity and duration of ocular pain, the tear film, ocular surface, and Meibomian gland examination, and OPAS. Patients with < 50% improvement in pain intensity after proparacaine challenge test were assigned to the central-dominant sensitization group (central group) and those with ≥50% improvement were assigned to the peripheral-dominant sensitization group (peripheral group). All variables were compared between the two groups. No significant differences were observed in age, sex, underlying diseases, history of ocular surgery, duration of ocular pain, tear film, ocular surface and Meibomian gland parameters (all p > 0.05). Ocular pain and non-ocular pain severity and the percentage of time spent thinking about non-ocular pain were significantly higher in the central group than in the peripheral group (all p < 0.05). Central group complained more commonly of a burnin...Continue Reading

References

Jun 1, 1989·The Clinical Journal of Pain·M P JensenR S Burns
Apr 1, 1996·Dermatologic Clinics·P J Lamey
Sep 9, 1999·Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology·M Bergdahl, J Bergdahl
Mar 20, 2004·Pain·Didier BouhassiraFrançois Boureau
Aug 9, 2008·The American Journal of Pathology·DeLisa FairweatherNoel R Rose
Feb 14, 2009·The Ocular Surface·Perry RosenthalDeborah S Jacobs
Apr 30, 2009·Annual Review of Neuroscience·Michael CostiganClifford J Woolf
Aug 29, 2009·The Journal of Pain : Official Journal of the American Pain Society·Alban Latremoliere, Clifford J Woolf
Oct 20, 2009·Cell·Allan I BasbaumDavid Julius
Dec 1, 2009·Progress in Retinal and Eye Research·R L Niederer, C N J McGhee
Jul 24, 2010·Lancet Neurology·Ralf BaronGunnar Wasner
Apr 1, 2011·Investigative Ophthalmology & Visual Science·Alan TomlinsonMurat Dogru
Oct 28, 2011·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Satu K Jääskeläinen
Feb 15, 2012·The Ocular Surface·Perry Rosenthal, David Borsook
Mar 1, 2012·Neuron·Christian A von HehnClifford J Woolf
Aug 3, 2013·JAMA Ophthalmology·Jelle VehofChristopher J Hammond
Sep 18, 2015·The British Journal of Ophthalmology·Anat GalorRoy C Levitt
Feb 18, 2016·Investigative Ophthalmology & Visual Science·Oriel SpiererAnat Galor
Jul 20, 2016·Journal of Optometry·Charles W Mcmonnies
Oct 11, 2016·Investigative Ophthalmology & Visual Science·Perry RosenthalEric A Moulton
Nov 5, 2016·Science·Cedric Peirs, Rebecca P Seal
Apr 9, 2017·Acta Ophthalmologica·Christophe BaudouinUNKNOWN ODISSEY European Consensus Group Members
May 22, 2017·American Journal of Ophthalmology·Vannarut SatitpitakulReza Dana
Jul 25, 2017·The Ocular Surface·Jennifer P CraigFiona Stapleton
Aug 12, 2017·The Ocular Surface·Jennifer P CraigDavid A Sullivan
Sep 1, 2017·Current Opinion in Allergy and Clinical Immunology·Hjalte H AndersenAnat Galor
Oct 23, 2017·Ophthalmology·Gabriela DieckmannPedram Hamrah
Sep 20, 2019·The British Journal of Ophthalmology·Andrew R RossDalia G Said

❮ Previous
Next ❯

Methods Mentioned

BETA
confocal microscopy

Software Mentioned

SPSS Statistics
Eye

Related Concepts

Related Feeds

Allergy and Asthma

Allergy and asthma are inflammatory disorders that are triggered by the activation of an allergen-specific regulatory t cell. These t cells become activated when allergens are recognized by allergen-presenting cells. Here is the latest research on allergy and asthma.