Clinical characteristics of epithelioid hemangioendothelioma: a single-center retrospective study

European Journal of Medical Research
Xin WuXiaodong He

Abstract

Epithelioid hemangioendothelioma (EHE) is a rare malignant vascular neoplasm with increasing incidence. However, its clinical characteristics remain unclear due to its low incidence. This study aimed to investigate the features of EHE. Patients with EHE treated at our institution between January 2000 and June 2018 were enrolled. Data including demographic characteristics, treatment patterns, pathological results, and prognosis were collected, and a retrospective database was constructed for analysis. The cohort comprised 33 patients with a mean age of 48.0 ± 16.0 years. Eighteen (54.5%) patients were asymptomatic. The laboratory tests were unremarkable except in five and two patients who had increased CA 125 and CA 19-9, respectively. Twenty-one patients underwent surgery, while 12 patients underwent only biopsy. The postoperative morbidity rate was 28.6% (6/21). The anatomical sites of the primary lesions varied. Immunohistochemical staining was positive for CD34 and CD31 in most patients. Twenty-six patients (78.8%) were followed up at a range of 1-201 months, and 6 patients died during this period. The 1-, 3-, and 5-year cumulative survival rates were 96.2%, 87.0%, and 75.3%, respectively. The patients who had metastases or ...Continue Reading

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Citations

Jul 23, 2020·VASA. Zeitschrift für Gefässkrankheiten·Fragiska SigalaNikolaos Alexakis
Apr 30, 2020·Thoracic Cancer·Wenpeng SongFeng Lin
Jan 18, 2020·Head and Neck Pathology·Uta FluckeKhin Thway
Nov 18, 2020·Current Problems in Diagnostic Radiology·Abdul RazikArun Kumar Gupta
Nov 22, 2020·The American Journal of Medicine·Amanda C MoaleSonye K Danoff
May 8, 2021·Rare Tumors·Ashley D HickmanAndrea E Wahner Hendrickson
May 25, 2021·American Journal of Clinical Oncology·Ilana R YurkiewiczNam Bui

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Methods Mentioned

BETA
biopsy
SMA
surgical resection

Software Mentioned

Statistical Package for Social Sciences software ( SPSS

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