Clinical characteristics of oldest-old patients with ischemic stroke

Rinshō shinkeigaku = Clinical neurology
Shizuka HaradaYukio Ando

Abstract

We divided acute ischemic stroke patients into an oldest old group (≥90 years, n = 414) and an elderly group (75-89 years, n = 1,927), and compared the clinical characteristics between the two groups. Female sex, early admission, severe stroke on admission, atrial fibrillation, and cardioembolic stoke were significantly more frequent in the oldest-old group. On the other hand, risk factors associated with atherosclerosis were less frequent in the oldest-old group. There were no differences in hyper-acute recanalization therapy between the two groups, whereas antithrombotic therapy for secondary prevention at discharge was introduced less frequently in the oldest-old group than in the elderly group. Death prior to discharge from the acute care hospital , and death at 3 months were significantly more frequent in the oldest-old group. Moreover, in the oldest old group, severe stroke and atrial fibrillation were independent predictors for both death prior to discharge from the acute care hospital and at 3 months after onset. Oldest-old stroke patients had poor outcome, although they had received aggressive treatment as same as elderly patients. Therefore, as the number of oldest-old stroke patients is increasing, the demand for coo...Continue Reading

References

Nov 1, 1995·Stroke; a Journal of Cerebral Circulation·R de HaanN Aaronson
Nov 22, 1997·Stroke; a Journal of Cerebral Circulation·A van StratenG A van den Bos
Jun 2, 2001·Stroke; a Journal of Cerebral Circulation·P D LydenUNKNOWN NINDS rtPA Stroke Study Group
Feb 13, 2004·Age and Ageing·Lars Peter KammersgaardUNKNOWN Copenhagen Stroke Study
Jun 17, 2008·Stroke; a Journal of Cerebral Circulation·Gustavo SaposnikUNKNOWN Stroke Outcome Research Canada (SORCan) Working Group
Oct 26, 2016·Stroke; a Journal of Cerebral Circulation·Nerses SanossianUNKNOWN FAST-MAG (Field Administration of Stroke Therapy-Magnesium) Investigators and Coordinators

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