Clinical characteristics of patients with hemodialysis-associated pneumonia compared to patients with non-hemodialysis community-onset pneumonia

Respiratory Medicine
Jong Hoo Lee, Jae Chol Moon

Abstract

The 2005 ATS/IDSA guidelines included hemodialysis-associated pneumonia (HDAP) as a category of healthcare-associated pneumonia (HCAP). However, the clinical epidemiology of HDAP has been not well established. This study aimed to evaluate the clinical and microbiological characteristics of HDAP patients compared to community-acquired pneumonia (CAP) or other HCAP except HDAP (O-HCAP). We conducted a retrospective observational study on HDAP patients who were admitted between January 2012 and December 2014. We compared clinical features, distribution of microorganisms, antibiotic regimens, and clinical outcomes among the three groups. A total of 914 patients, comprised of 595 patients with CAP, 24 with HDAP, and 295 with O-HCAP, were evaluated. The median PSI score of the HDAP group was higher than that of the CAP group and similar to that of the O-HCAP group. The major pathogens of the HDAP group were Staphylococcus aureus and Klebsiella pneumoniae. The isolation rate of multidrug-resistant (MDR) pathogens and total in-hospital mortality of the HDAP group was similar to those of the CAP group (8.3% vs. 6.8%, p = 1.000 and 4.1% vs. 7.5%, p = 0.821, respectively). Otherwise, the isolation rate of MDR pathogens and total in-hospit...Continue Reading

References

Jul 29, 2003·The European Respiratory Journal·T J MarrieD H Johnson
Mar 10, 2004·Archives of Internal Medicine·Beatriz RosónFrancesc Gudiol
Feb 9, 2005·American Journal of Respiratory and Critical Care Medicine·UNKNOWN American Thoracic Society, UNKNOWN Infectious Diseases Society of America
Feb 6, 2007·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Lionel A MandellUNKNOWN American Thoracic Society
Aug 8, 2007·Antimicrobial Agents and Chemotherapy·Scott T MicekMarin H Kollef
Oct 14, 2009·Thorax·W S LimUNKNOWN Pneumonia Guidelines Committee of the BTS Standards of Care Committee
Oct 28, 2009·Respirology : Official Journal of the Asian Pacific Society of Respirology·UNKNOWN Japanese Respiratory Society
Mar 4, 2011·Journal of Infection and Chemotherapy : Official Journal of the Japan Society of Chemotherapy·Satoshi KawasakiIchiei Narita
Mar 15, 2011·BMC Infectious Diseases·Ji Ye JungYoung Ae Kang
May 21, 2011·Journal of Infection and Chemotherapy : Official Journal of the Japan Society of Chemotherapy·Yuka Yamagishi, Hiroshige Mikamo
Jun 22, 2011·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·James D ChalmersAdam T Hill
Nov 2, 2011·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·M WoodheadUNKNOWN Joint Taskforce of the European Respiratory Society and European Society for Clinical Microbiology and Infectious Diseases
Aug 15, 2012·Journal of the American Medical Directors Association·Hon Ming MaJean Woo
Oct 17, 2012·Respirology : Official Journal of the Asian Pacific Society of Respirology·Stephanie Parks Taylor, Brice T Taylor
Nov 17, 2012·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Byeong-Ho JeongKyeongman Jeon
May 18, 2013·The Korean Journal of Internal Medicine·Young-Ki LeeDae Joong Kim
Jul 17, 2013·American Journal of Respiratory and Critical Care Medicine·Yuichiro ShindoYoshinori Hasegawa
Nov 7, 2013·Respiratory Care·Adamantia LiapikouUNKNOWN Community-Acquired Pneumonia Organization (CAPO) Investigators
Nov 26, 2013·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·James D ChalmersSantiago Ewig
Jun 25, 2014·Antimicrobial Agents and Chemotherapy·Alan E GrossAndre C Kalil
Jul 15, 2015·The New England Journal of Medicine·Seema JainUNKNOWN CDC EPIC Study Team

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.