Clinical characteristics of pediatric SARS-CoV-2 infection and coronavirus disease 2019 (COVID-19) in Kuwait.

Journal of Medical Virology
Danah AlsharrahMohammad Alghounaim

Abstract

Clinical presentation of coronavirus disease-2019 (COVID-19) ranges from asymptomatic to severe and life-threatening. National-level registries found that children, generally, have less severe disease when compared with adults. However, most asymptomatically infected children will not present to hospital and may be missed. We aimed to describe the clinical characteristics in pediatric COVID-19 patients in Kuwait, and to estimate the potential duration of viral shedding. A retrospective cohort study was performed in Jaber Alahmad Hospital (JAH) from February 29 to April 30, 2020. During the study period and as part of the public health measures, all severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-infected patients from 1 month to 18 years old, regardless of symptoms, were hospitalized at JAH, and were included. Polymerase chain reaction (PCR) negativity was defined as having two consecutive negative PCR results from a respiratory specimen. Descriptive statistics and multivariable regression analyses were performed. We found that 67.9% (95% CI, 59.4%-75.3%) of 134 SARS-CoV-2-infected children were asymptomatic. Median PCR positivity was 15 days and did not vary with symptoms. Among patients who had laboratory investi...Continue Reading

References

Jan 19, 2019·Journal of the Pediatric Infectious Diseases Society·Jesse PapenburgBrett Burstein
Mar 18, 2020·Pediatrics·Yuanyuan DongShilu Tong
Mar 19, 2020·The New England Journal of Medicine·Xiaoxia LuUNKNOWN Chinese Pediatric Novel Coronavirus Study Team
May 21, 2020·JAMA : the Journal of the American Medical Association·Supinda BunyavanichAlfin Vicencio
Jun 4, 2020·Pediatric Pulmonology·Tiago H de SouzaMarcelo B Brandão
Jul 1, 2020·The Lancet Child & Adolescent Health·Florian GötzingerUNKNOWN ptbnet COVID-19 Study Group

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Citations

Aug 12, 2021·Proceedings of the National Academy of Sciences of the United States of America·Pratha SahAlison P Galvani
Aug 21, 2021·3D Printing in Medicine·Ameerah AlazemiSalman Al-Sabah

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