Abstract
The patient's clinical features at hemodialysis initiation can affect their prognosis in the subsequent dialysis period; however, these features have not been fully elucidated in very elderly subjects. The purpose of this study was to clarify the clinical characteristics associated with cardiovascular and chronic kidney disease at hemodialysis initiation. Twenty consecutive very elderly patients with end-stage renal disease (ESRD) (≥80 years; VE group) and 35 consecutive control patients with ESRD (<60 years; control group) were included in this study. All patients had started maintenance hemodialysis therapy at our institution. We evaluated the clinical characteristics, laboratory data, thoracic aortic calcification (TAC) and echocardiographic parameters, including aortic valve calcification (AVC), mitral valve calcification and mitral annular calcification (MAC). The diastolic blood pressure was significantly lower and pulse pressure values were significantly higher in the VE group than in the control group, whereas the estimated glomerular filtration rate and cardiac function were comparable between the two groups. Despite having lower serum phosphate and calcium-phosphate product levels, the VE group exhibited more severe T...Continue Reading
References
Apr 1, 1977·Circulation·R B Devereux, N Reichek
Jul 1, 1996·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·P S ParfreyP E Barre
Mar 20, 1998·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·G T Obrador, B J Pereira
Oct 9, 2001·Lancet·J C KorevaarUNKNOWN Netherlands Cooperative Study on the Adequacy of Dialysis Study Group
Oct 20, 2005·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Cécile CouchoudChristian Jacquelinet
Feb 7, 2007·Annals of Internal Medicine·Manjula KurellaGlenn M Chertow
Apr 7, 2007·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Fliss E M MurtaghFiona E Harris
Jul 10, 2007·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Cécile CouchoudBénédicte Stengel
Mar 28, 2008·The New England Journal of Medicine·Robert DetranoRichard A Kronmal
Dec 20, 2008·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Cécile CouchoudUNKNOWN French Renal Epidemiology and Information Network (REIN) registry
Jun 29, 2010·The New England Journal of Medicine·Bruce A CooperUNKNOWN IDEAL Study
May 11, 2011·Clinical Journal of the American Society of Nephrology : CJASN·Steven RosanskyWilliam F Clark
Jun 28, 2011·Clinical Journal of the American Society of Nephrology : CJASN·Paolo RaggiPaul Muntner
Nov 18, 2011·Kidney International·Manjula Kurella TamuraAnn M O'Hare
Dec 4, 2013·Nature Reviews. Nephrology·Tushar J VachharajaniTimmy C Lee