Clinical characteristics with an impact on ADL functions of PD patients with cognitive impairment indicative of dementia

PloS One
Inga Liepelt-ScarfoneDaniela Berg

Abstract

Dementia in Parkinson's disease (PD) is defined as cognitive decline severe enough to affect activities of daily living function (ADL). The aim of our exploratory study was to compare two groups of PD patients. Both groups had cognitive deficits severe enough to justify diagnosis of dementia, but they differed according to caregivers' rating on ADL dysfunction. Parameters which differed between the two groups were interpreted to affect the caregivers' perception of ADL dysfunction in PD patients with cognitive impairment indicative of Parkinson's disease dementia. Thirty of 131 Parkinson's disease patients fulfilled the Movement Disorders Society Task Force - recommended, cognitive Level-I-criteria for dementia. According to standardized caregiver ratings, volunteers were grouped into 18 patients with (ADL-) and 12 without instrumental activities of daily living dysfunction (ADL+). Caregiver activities of daily living function ratings closely correlated with self-estimates of patients and those of physician (p<0.001). ADL- patients performed worse on tests assessing visual-construction (p<0.05) and attention (p=0.03) than ADL+ patients. Moreover, the postural instability and gait disorder subtype was more frequent in ADL- patie...Continue Reading

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Citations

Nov 21, 2020·Journal of Alzheimer's Disease : JAD·Sara BeckerUNKNOWN Alzheimer’s Disease Neuroimaging Initiative
Jan 6, 2021·The American Journal of Occupational Therapy : Official Publication of the American Occupational Therapy Association·Sujatha E RajMandy Stanley
Jun 11, 2021·Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·Sara BeckerInga Liepelt-Scarfone

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Software Mentioned

Visual Object and Space Perception Battery ( VOSP )
TF
SPSS Statistics
MDS

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